ethyl (2S)-3-(4-hydroxyphenyl)-2-[6-(5-methoxy-1H-indol-3-yl)-6-(4-methoxyphenyl)-4-oxohexanamido]propanoate

Base Information

• Chemical Name: ethyl (2S)-3-(4-hydroxyphenyl)-2-[6-(5-methoxy-1H-indol-3-yl)-6-(4-methoxyphenyl)-4-oxohexanamido]propanoate
• CAS No.: 1072881-37-8
• Molecular Formula: C₃₃H₃₆N₂O₇
• Molecular Weight: 572.658
• Mol file: 1072881-37-8.mol

Synonyms:ethyl (2S)-3-(4-hydroxyphenyl)-2-[6-(5-methoxy-1H-indol-3-yl)-6-(4-methoxyphenyl)-4-oxohexanamido]propanoate

Chemical Property of ethyl (2S)-3-(4-hydroxyphenyl)-2-[6-(5-methoxy-1H-indol-3-yl)-6-(4-methoxyphenyl)-4-oxohexanamido]propanoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of ethyl (2S)-3-(4-hydroxyphenyl)-2-[6-(5-methoxy-1H-indol-3-yl)-6-(4-methoxyphenyl)-4-oxohexanamido]propanoate

There total 1 articles about ethyl (2S)-3-(4-hydroxyphenyl)-2-[6-(5-methoxy-1H-indol-3-yl)-6-(4-methoxyphenyl)-4-oxohexanamido]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

6-(5-methoxy-1H-indol-3-yl)-6-(4-methoxyphenyl)-4-oxohexanoic acid (1072881-33-4) + L-tyrosine ethyl ester (949-67-7) → ethyl (2S)-3-(4-hydroxyphenyl)-2-[6-(5-methoxy-1H-indol-3-yl)-6-(4-methoxyphenyl)-4-oxohexanamido]propanoate (1072881-37-8)

Guidance literature:

With 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

DOI:10.1016/j.bmc.2008.07.084

Reference yield: 82.0%

ethyl (2S)-3-(4-hydroxyphenyl)-2-[6-(5-methoxy-1H-indol-3-yl)-6-(4-methoxyphenyl)-4-oxohexanamido]propanoate (1072881-37-8) → C31H32N2O7 (1072881-21-0)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; ethanol; at 20 ℃; for 3h;

DOI:10.1016/j.bmc.2008.07.084

upstream raw materials:

6-(5-methoxy-1H-indol-3-yl)-6-(4-methoxyphenyl)-4-oxohexanoic acid

L-tyrosine ethyl ester

Downstream raw materials:

C₃₁H₃₂N₂O₇