Oxiranecarboxylic acid, 3-propyl-, methyl ester, (2S-trans)- (9CI)

Base Information

• Chemical Name: Oxiranecarboxylic acid, 3-propyl-, methyl ester, (2S-trans)- (9CI)
• CAS No.: 107796-99-6
• Molecular Formula: C7H12 O3
• Molecular Weight: 144.17
• Mol file: 107796-99-6.mol

Synonyms:Oxiranecarboxylicacid, 3-propyl-, methyl ester, (2S,3R)- (9CI); Oxiranecarboxylic acid,3-propyl-, methyl ester, (2S-trans)-

Chemical Property of Oxiranecarboxylic acid, 3-propyl-, methyl ester, (2S-trans)- (9CI)

Chemical Property:

• PSA: 38.83000
• LogP: 0.72690

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Oxiranecarboxylic acid, 3-propyl-, methyl ester, (2S-trans)- (9CI)

There total 7 articles about Oxiranecarboxylic acid, 3-propyl-, methyl ester, (2S-trans)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Methyl (2R,3R)-2-chloro-3-hydroxyhexanoate (959709-92-3) → Methyl (2S,3R)-(+)-3-propyloxirane-2-carboxylate (107796-99-6,117709-02-1,173828-92-7)

Guidance literature:

With potassium carbonate; In ethanol; at 15 ℃; for 14h;

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + (2R,3R)-2,3-epoxy-1-hexanol (92418-71-8) → Methyl (2S,3R)-(+)-3-propyloxirane-2-carboxylate (107796-99-6,117709-02-1,173828-92-7)

Guidance literature:

With ruthenium trichloride; sodium periodate; Yield given. Multistep reaction; 1.) carbon tetrachloride, acetonitrile, water, room temperature, 1.5 h; 2.) ether, 3 h;

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + (2R,3R)-2,3-epoxy-1-hexanol (92418-71-8) → Methyl (2R,3S)-(-)-3-propyloxirane-2-carboxylate (100992-81-2,117709-02-1,173828-92-7) + Methyl (2S,3R)-(+)-3-propyloxirane-2-carboxylate (107796-99-6,117709-02-1,173828-92-7)

Guidance literature:

With ruthenium trichloride; sodium periodate; Yield given. Multistep reaction. Yields of byproduct given; 1) CCl₄, CH₃CN, water, 1.5 h, 2) ether;

DOI:10.1002/recl.19921110101

upstream raw materials:

diazomethane

2,3-epoxyhexanol

(2R,3R)-2,3-epoxy-1-hexanol

3-propylepoxyethane-2-carboxylic acid

Downstream raw materials:

(2R,3S)-1-(3,5-Dinitro-benzoyl)-3-propyl-aziridine-2-carboxylic acid methyl ester

(S)-γ-Propyl-γ-butyrolactone