O-(2,3,4-Tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-4)>-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose

Base Information

Chemical Name:O-(2,3,4-Tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-4)>-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose
CAS No.:162710-69-2
Molecular Formula:C₆₃H₆₉N₃O₁₃
Molecular Weight:1076.25
Hs Code.:

O-(2,3,4-Tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-<O-(3-O-allyl-2,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1->4)>-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose

Synonyms:O-(2,3,4-Tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-4)>-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose

Suppliers and Price of O-(2,3,4-Tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-4)>-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of O-(2,3,4-Tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-4)>-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of O-(2,3,4-Tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-4)>-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose

There total 18 articles about O-(2,3,4-Tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-4)>-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 33639-77-9
perbenzyl fucosyl bromide

: 162710-56-7
O-(3-O-Allyl-2,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1->4)-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose

: 162710-69-2
O-(2,3,4-Tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-4)>-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose

Guidance literature:: With 4 A molecular sieve; mercury dibromide; In dichloromethane; 1.) r.t., 1 h, 2.) r.t., 7 h;
DOI:10.1021/jo00111a008

Reference yield:

: 203435-09-0
2,3,4,6-tetra-O-benzoyl-α,b-D-galactopyranosyl trichloroacetimidate

: 162710-69-2
O-(2,3,4-Tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-4)>-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose

Guidance literature:: Multi-step reaction with 8 steps

1: 84 percent / trimethylsilyl triflate, 4 Angstroem molecular sieves / CH₂Cl₂ / 1.) -20 deg C, 2 h, 2.) -20 deg C to 0 deg C, 2 h

2: 99 percent / NaOMe / methanol / 2 h / Ambient temperature

3: 1.) dibutyltin oxide, N-methylimidazole, 3 Angstroem molecular sieves / 1.) CH₃CN, 80 deg C, 2 h, 2.) 80 deg C, 3 h

4: 83 percent / NaH / dimethylformamide / 1.) r.t., 1 h, 2.) r.t., 2 h

5: 92 percent / 80percent aq. AcOH / 2 h / 75 °C

6: pyridine / 1.5 h / -40 °C

7: NaN₃ / dimethylformamide / 24 h / Ambient temperature

8: 68 percent / HgBr₂, 4 Angstroem molecular sieves / CH₂Cl₂ / 1.) r.t., 1 h, 2.) r.t., 7 h

With pyridine; 1-methyl-1H-imidazole; sodium azide; trimethylsilyl trifluoromethanesulfonate; 3 A molecular sieve; 4 A molecular sieve; sodium methylate; sodium hydride; di(n-butyl)tin oxide; acetic acid; mercury dibromide; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo00111a008

Reference yield:

: 100-39-0
benzyl bromide

: 162710-69-2
O-(2,3,4-Tri-O-benzyl-α-L-fucopyranosyl)-(1->3)-4)>-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose

Guidance literature:: Multi-step reaction with 5 steps

1: 83 percent / NaH / dimethylformamide / 1.) r.t., 1 h, 2.) r.t., 2 h

2: 92 percent / 80percent aq. AcOH / 2 h / 75 °C

3: pyridine / 1.5 h / -40 °C

4: NaN₃ / dimethylformamide / 24 h / Ambient temperature

5: 68 percent / HgBr₂, 4 Angstroem molecular sieves / CH₂Cl₂ / 1.) r.t., 1 h, 2.) r.t., 7 h

With pyridine; sodium azide; 4 A molecular sieve; sodium hydride; acetic acid; mercury dibromide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo00111a008