Technology Process of (2R,3R)-2-((benzyloxy)methyl)-3-ethyl-2-methyloxirane
There total 3 articles about (2R,3R)-2-((benzyloxy)methyl)-3-ethyl-2-methyloxirane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetra-(n-butyl)ammonium iodide; sodium hydride;
In
tetrahydrofuran;
at 0 - 20 ℃;
DOI:10.1021/jo0704762
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 4 Angstroem molecular sueves; Ti(OiPr)4; D-(-)-diisopropyl tartrate / CH2Cl2 / -25 °C
2: 92 percent / NaH; PTC; TBAI / tetrahydrofuran / 0 - 20 °C
With
titanium(IV) isopropylate; tetra-(n-butyl)ammonium iodide; sodium hydride; D-(-)-diisopropyl tartrate;
In
tetrahydrofuran; dichloromethane;
1: Sharpless asymmetric epoxidation;
DOI:10.1021/jo0704762
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 85 percent / LiAlH4; AlCl3 / diethyl ether / 3 h / 0 °C
2: 4 Angstroem molecular sueves; Ti(OiPr)4; D-(-)-diisopropyl tartrate / CH2Cl2 / -25 °C
3: 92 percent / NaH; PTC; TBAI / tetrahydrofuran / 0 - 20 °C
With
titanium(IV) isopropylate; lithium aluminium tetrahydride; aluminium trichloride; tetra-(n-butyl)ammonium iodide; sodium hydride; D-(-)-diisopropyl tartrate;
In
tetrahydrofuran; diethyl ether; dichloromethane;
2: Sharpless asymmetric epoxidation;
DOI:10.1021/jo0704762
