Technology Process of (E)-1-(2-hydroxy-4-methoxy-3-(3-methylbuta-1,3-dienyl)phenyl)ethanone
There total 4 articles about (E)-1-(2-hydroxy-4-methoxy-3-(3-methylbuta-1,3-dienyl)phenyl)ethanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl-ammonium chloride; sodium hydrogencarbonate; palladium dichloride;
In
N,N-dimethyl-formamide;
at 100 ℃;
for 4h;
DOI:10.1016/j.tetlet.2015.07.042
- Guidance literature:
-
Multi-step reaction with 3 steps
1: iodine; potassium iodate / ethanol; water / 24 h / 20 °C
2: potassium carbonate; methyl iodide / acetone / 8 h / 20 °C
3: palladium dichloride; tetrabutyl-ammonium chloride; sodium hydrogencarbonate / N,N-dimethyl-formamide / 4 h / 100 °C
With
potassium iodate; tetrabutyl-ammonium chloride; iodine; sodium hydrogencarbonate; potassium carbonate; palladium dichloride; methyl iodide;
In
ethanol; water; N,N-dimethyl-formamide; acetone;
3: |Heck Reaction;
DOI:10.1016/j.tetlet.2015.07.042
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium carbonate; methyl iodide / acetone / 8 h / 20 °C
2: palladium dichloride; tetrabutyl-ammonium chloride; sodium hydrogencarbonate / N,N-dimethyl-formamide / 4 h / 100 °C
With
tetrabutyl-ammonium chloride; sodium hydrogencarbonate; potassium carbonate; palladium dichloride; methyl iodide;
In
N,N-dimethyl-formamide; acetone;
2: |Heck Reaction;
DOI:10.1016/j.tetlet.2015.07.042
