methyl 4'-(2-{[(2R)-2-[6-(acetylamino)-3-pyridinyl]-2-{[tert-butyl(dimethyl)siltl]oxy}ethyl](tert-butoxycarbonyl)amino}ethyl)-3-isobutyl-4-biphenylcarboxylate

Base Information

Chemical Name:methyl 4'-(2-{[(2R)-2-[6-(acetylamino)-3-pyridinyl]-2-{[tert-butyl(dimethyl)siltl]oxy}ethyl](tert-butoxycarbonyl)amino}ethyl)-3-isobutyl-4-biphenylcarboxylate
CAS No.:945548-92-5
Molecular Formula:C₄₀H₅₇N₃O₆Si
Molecular Weight:703.995
Hs Code.:

methyl 4'-(2-{[(2R)-2-[6-(acetylamino)-3-pyridinyl]-2-{[tert-butyl(dimethyl)siltl]oxy}ethyl](tert-butoxycarbonyl)amino}ethyl)-3-isobutyl-4-biphenylcarboxylate

Synonyms:methyl 4'-(2-{[(2R)-2-[6-(acetylamino)-3-pyridinyl]-2-{[tert-butyl(dimethyl)siltl]oxy}ethyl](tert-butoxycarbonyl)amino}ethyl)-3-isobutyl-4-biphenylcarboxylate

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Chemical Property of methyl 4'-(2-{[(2R)-2-[6-(acetylamino)-3-pyridinyl]-2-{[tert-butyl(dimethyl)siltl]oxy}ethyl](tert-butoxycarbonyl)amino}ethyl)-3-isobutyl-4-biphenylcarboxylate

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Technology Process of methyl 4'-(2-{[(2R)-2-[6-(acetylamino)-3-pyridinyl]-2-{[tert-butyl(dimethyl)siltl]oxy}ethyl](tert-butoxycarbonyl)amino}ethyl)-3-isobutyl-4-biphenylcarboxylate

There total 1 articles about methyl 4'-(2-{[(2R)-2-[6-(acetylamino)-3-pyridinyl]-2-{[tert-butyl(dimethyl)siltl]oxy}ethyl](tert-butoxycarbonyl)amino}ethyl)-3-isobutyl-4-biphenylcarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 855482-81-4
[3-isobutyl-4-(methoxycarbonyl)phenyl]boronic acid

: 855482-10-9
tert-butyl [(2R)-2-[6-(acetylamino)-3-pyridinyl]-2-{[tert-butyl(dimethyl)silyl]oxy}ethyl][2-(4-bromophenyl)ethyl]carbamate

: 945548-92-5
methyl 4'-(2-{[(2R)-2-[6-(acetylamino)-3-pyridinyl]-2-{[tert-butyl(dimethyl)siltl]oxy}ethyl](tert-butoxycarbonyl)amino}ethyl)-3-isobutyl-4-biphenylcarboxylate

Guidance literature:: With 1,1'-bis-(diphenylphosphino)ferrocene; 1,1'-bis(diphenylphosphino)ferrocene-palladium(ii)dichloride-chloroform adduct; sodium carbonate; In water; N,N-dimethyl-formamide; at 80 ℃; for 3h; Inert atmosphere;
DOI:10.1021/jm8000345