tert-butyl-((2S,6S)-2,6-dimethyltridecyloxy)-diphenyl silane

Base Information

• Chemical Name: tert-butyl-((2S,6S)-2,6-dimethyltridecyloxy)-diphenyl silane
• CAS No.: 887278-78-6
• Molecular Formula: C₃₁H₅₀OSi
• Molecular Weight: 466.823
• Mol file: 887278-78-6.mol

Synonyms:tert-butyl-((2S,6S)-2,6-dimethyltridecyloxy)-diphenyl silane

Chemical Property of tert-butyl-((2S,6S)-2,6-dimethyltridecyloxy)-diphenyl silane

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of tert-butyl-((2S,6S)-2,6-dimethyltridecyloxy)-diphenyl silane

There total 14 articles about tert-butyl-((2S,6S)-2,6-dimethyltridecyloxy)-diphenyl silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

8-(tert-butyldiphenylsilanyloxy)-(3R,7S)-3,7-dimethyloctyl p-toluenesulfonate (887278-77-5) + 1-Bromopentane (110-53-2) → tert-butyl-((2S,6S)-2,6-dimethyltridecyloxy)-diphenyl silane (887278-78-6)

Guidance literature:

1-Bromopentane; With magnesium; In tetrahydrofuran; at 45 ℃; for 1h;

8-(tert-butyldiphenylsilanyloxy)-(3R,7S)-3,7-dimethyloctyl p-toluenesulfonate; With copper(I) bromide dimethylsulfide complex; In tetrahydrofuran; at -78 - 0 ℃;

DOI:10.1021/ja060499i

Reference yield: 90.0%

1-(tert-butyldiphenylsilyloxy)-(2S,6S)-2,6-dimethyl-4-tridecene → tert-butyl-((2S,6S)-2,6-dimethyltridecyloxy)-diphenyl silane (887278-78-6)

Guidance literature:

With copper(II) sulfate; hydrazine; In ethanol; at 70 ℃; for 15h; Reagent/catalyst; Time; Temperature;

DOI:10.1016/j.tet.2013.09.020

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → tert-butyl-((2S,6S)-2,6-dimethyltridecyloxy)-diphenyl silane (887278-78-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 95 percent / imidazole / dimethylformamide / 0.5 h / 20 °C

2.1: 86 percent / pyridine / 36 h / 0 °C

3.1: Mg / tetrahydrofuran / 1 h / 45 °C

3.2: 97 percent / CuBr*SMe₂ / tetrahydrofuran / -78 - 0 °C

With pyridine; 1H-imidazole; magnesium; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1021/ja060499i

upstream raw materials:

8-(tert-butyldiphenylsilanyloxy)-(3R,7S)-3,7-dimethyloctyl p-toluenesulfonate

1-Bromopentane

tert-butylchlorodiphenylsilane

methyl 8-hydroxy-(3R,7S)-3,7-dimethyloctanoic acid

Downstream raw materials:

tert-butyldiphenyl-(2S,6R,10S,14S)-2,6,10,14-tetramethylhenicos-8-enyloxysilane