tert-butyl<<2-bromo-3,5-bis<(triisopropylsilyl)oxy>benzyl>oxy>dimethylsilane

Base Information

• Chemical Name: tert-butyl<<2-bromo-3,5-bis<(triisopropylsilyl)oxy>benzyl>oxy>dimethylsilane
• CAS No.: 169821-91-4
• Molecular Formula: C₃₁H₆₁BrO₃Si₃
• Molecular Weight: 645.984
• Mol file: 169821-91-4.mol

Synonyms:tert-butyl<<2-bromo-3,5-bis<(triisopropylsilyl)oxy>benzyl>oxy>dimethylsilane

Chemical Property of tert-butyl<<2-bromo-3,5-bis<(triisopropylsilyl)oxy>benzyl>oxy>dimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl<<2-bromo-3,5-bis<(triisopropylsilyl)oxy>benzyl>oxy>dimethylsilane

There total 7 articles about tert-butyl<<2-bromo-3,5-bis<(triisopropylsilyl)oxy>benzyl>oxy>dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

tert-butyldimethylsilyl chloride (18162-48-6) + 2-bromo-3,5-bis<(triisopropylsilyl)oxy>benzyl alcohol (174464-92-7) → tert-butyl<<2-bromo-3,5-bis<(triisopropylsilyl)oxy>benzyl>oxy>dimethylsilane (169821-91-4)

Guidance literature:

With 1H-imidazole; dmap; In dichloromethane;

DOI:10.1039/c39950001147

Reference yield:

1-carbomethoxy-3,5-dihydroxybenzene (2150-44-9) → tert-butyl<<2-bromo-3,5-bis<(triisopropylsilyl)oxy>benzyl>oxy>dimethylsilane (169821-91-4)

Guidance literature:

Multi-step reaction with 4 steps

1: DMAP; imidazole / dimethylformamide

2: LiAlH₄ / diethyl ether

3: NBS / CCl₄

4: DMAP; imidazole / dimethylformamide

With 1H-imidazole; dmap; N-Bromosuccinimide; lithium aluminium tetrahydride; In tetrachloromethane; diethyl ether; N,N-dimethyl-formamide;

DOI:10.1055/s-2001-13399

Reference yield:

3,5-bis<(triisopropylsilyl)oxy>benzyl alcohol (174464-90-5) → tert-butyl<<2-bromo-3,5-bis<(triisopropylsilyl)oxy>benzyl>oxy>dimethylsilane (169821-91-4)

Guidance literature:

Multi-step reaction with 2 steps

1: NBS / CCl₄

2: DMAP; imidazole / dimethylformamide

With 1H-imidazole; dmap; N-Bromosuccinimide; In tetrachloromethane; N,N-dimethyl-formamide;

DOI:10.1055/s-2001-13399

upstream raw materials:

tert-butyldimethylsilyl chloride

2-bromo-3,5-bis<(triisopropylsilyl)oxy>benzyl alcohol

triisopropylsilyl chloride

1-carbomethoxy-3,5-dihydroxybenzene