(4S,5S)-2-<(S)-1-(N,N-dimethylhydrazino)pentyl>-1,3-dimethyl-4,5-diphenylimidazolidine

Base Information

• Chemical Name: (4S,5S)-2-<(S)-1-(N,N-dimethylhydrazino)pentyl>-1,3-dimethyl-4,5-diphenylimidazolidine
• CAS No.: 133643-24-0
• Molecular Formula: C₂₄H₃₆N₄
• Molecular Weight: 380.577
• Mol file: 133643-24-0.mol

Synonyms:(4S,5S)-2-<(S)-1-(N,N-dimethylhydrazino)pentyl>-1,3-dimethyl-4,5-diphenylimidazolidine

Chemical Property of (4S,5S)-2-<(S)-1-(N,N-dimethylhydrazino)pentyl>-1,3-dimethyl-4,5-diphenylimidazolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4S,5S)-2-<(S)-1-(N,N-dimethylhydrazino)pentyl>-1,3-dimethyl-4,5-diphenylimidazolidine

There total 2 articles about (4S,5S)-2-<(S)-1-(N,N-dimethylhydrazino)pentyl>-1,3-dimethyl-4,5-diphenylimidazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

n-butyllithium (109-72-8,29786-93-4) + (4S,5S)-2--1,3-dimethyl-4,5-diphenylimidazolidine (133643-21-7) → (4S,5S)-2-<(S)-1-(N,N-dimethylhydrazino)pentyl>-1,3-dimethyl-4,5-diphenylimidazolidine (133643-24-0)

Guidance literature:

In tetrahydrofuran; at -70 - 20 ℃; for 0.5h;

DOI:10.1055/s-1995-4042

Reference yield:

(S,S)-N,N'-dimethyl-1,2-diphenylethane-1,2-diamine (22751-68-4,60508-97-6,60509-62-8,70749-06-3,118628-68-5) → (4S,5S)-2-<(S)-1-(N,N-dimethylhydrazino)pentyl>-1,3-dimethyl-4,5-diphenylimidazolidine (133643-24-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent

2: 60 percent / diethyl ether / -78 deg C to r.t.

In diethyl ether;

DOI:10.1016/S0040-4039(00)92036-7

Reference yield: 60.0%

(4S,5S)-2-<(S)-1-(N,N-dimethylhydrazino)pentyl>-1,3-dimethyl-4,5-diphenylimidazolidine (133643-24-0) → (4S,5S)-2-<(S)-1-aminopentyl>-1,3-dimethyl-4,5-diphenylimidazolidine

Guidance literature:

With hydrogen; W-2 Raney Ni; In methanol; Irradiation;

DOI:10.1055/s-1995-4042

upstream raw materials:

n-butyllithium

(4S,5S)-2--1,3-dimethyl-4,5-diphenylimidazolidine

(S,S)-N,N'-dimethyl-1,2-diphenylethane-1,2-diamine