(1S,2R,3S,4R)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid 2-tert-butyl ester 3-((S)-1-phenyl-ethyl) ester

Base Information

Chemical Name:(1S,2R,3S,4R)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid 2-tert-butyl ester 3-((S)-1-phenyl-ethyl) ester
CAS No.:162361-96-8
Molecular Formula:C₂₁H₂₆O₄
Molecular Weight:342.435
Hs Code.:

Synonyms:(1S,2R,3S,4R)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid 2-tert-butyl ester 3-((S)-1-phenyl-ethyl) ester

Suppliers and Price of (1S,2R,3S,4R)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid 2-tert-butyl ester 3-((S)-1-phenyl-ethyl) ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2R,3S,4R)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid 2-tert-butyl ester 3-((S)-1-phenyl-ethyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2R,3S,4R)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid 2-tert-butyl ester 3-((S)-1-phenyl-ethyl) ester

There total 3 articles about (1S,2R,3S,4R)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid 2-tert-butyl ester 3-((S)-1-phenyl-ethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 542-92-7,25568-84-7,7313-32-8
cyclopenta-1,3-diene

: 162361-92-4
tert-butyl (S)-α-phenethyl maleate

: (1R,2S,3R,4S)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid 2-tert-butyl ester 3-((S)-1-phenyl-ethyl) ester

: 162361-96-8
(1S,2R,3S,4R)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid 2-tert-butyl ester 3-((S)-1-phenyl-ethyl) ester

Guidance literature:: With boron trifluoride diethyl etherate; In dichloromethane; at -78 ℃; for 1h; Yield given. Yields of byproduct given;
DOI:10.1021/ja00093a013

Reference yield:

: 1445-91-6
(S)-1-phenylethanol

: 162361-96-8
(1S,2R,3S,4R)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid 2-tert-butyl ester 3-((S)-1-phenyl-ethyl) ester

Guidance literature:: Multi-step reaction with 3 steps

1: toluene / Heating

2: conc. H₂SO₄ / CH₂Cl₂ / Ambient temperature

3: BF₃*OEt₂ / CH₂Cl₂ / 1 h / -78 °C

With sulfuric acid; boron trifluoride diethyl etherate; In dichloromethane; toluene;
DOI:10.1021/ja00093a013

Reference yield:

: 165304-73-4
(Z)-But-2-enedioic acid mono-((S)-1-phenyl-ethyl) ester

: 162361-96-8
(1S,2R,3S,4R)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid 2-tert-butyl ester 3-((S)-1-phenyl-ethyl) ester

Guidance literature:: Multi-step reaction with 2 steps

1: conc. H₂SO₄ / CH₂Cl₂ / Ambient temperature

2: BF₃*OEt₂ / CH₂Cl₂ / 1 h / -78 °C

With sulfuric acid; boron trifluoride diethyl etherate; In dichloromethane;
DOI:10.1021/ja00093a013