(2S,4S)-2-hydroxymethyl-4-(4-methylbenzenesulfonyl)amino-1-phenylpyrrolidine

Base Information

Chemical Name:(2S,4S)-2-hydroxymethyl-4-(4-methylbenzenesulfonyl)amino-1-phenylpyrrolidine
CAS No.:1304774-17-1
Molecular Formula:C₁₈H₂₂N₂O₃S
Molecular Weight:346.45
Hs Code.:

Synonyms:(2S,4S)-2-hydroxymethyl-4-(4-methylbenzenesulfonyl)amino-1-phenylpyrrolidine

Suppliers and Price of (2S,4S)-2-hydroxymethyl-4-(4-methylbenzenesulfonyl)amino-1-phenylpyrrolidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,4S)-2-hydroxymethyl-4-(4-methylbenzenesulfonyl)amino-1-phenylpyrrolidine

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Technology Process of (2S,4S)-2-hydroxymethyl-4-(4-methylbenzenesulfonyl)amino-1-phenylpyrrolidine

There total 16 articles about (2S,4S)-2-hydroxymethyl-4-(4-methylbenzenesulfonyl)amino-1-phenylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1304774-10-4
methyl (2S,4S)-4-(4-methylbenzenesulfonyl)amino-5-oxo-1-phenylprolinate

: 1304774-17-1
(2S,4S)-2-hydroxymethyl-4-(4-methylbenzenesulfonyl)amino-1-phenylpyrrolidine

Guidance literature:: With dimethylsulfide borane complex; In tetrahydrofuran; at 0 - 40 ℃; for 168.5h; chemoselective reaction; Inert atmosphere;
DOI:10.1002/ejoc.201100049

Reference yield: 44.0%

: 1304774-10-4
methyl (2S,4S)-4-(4-methylbenzenesulfonyl)amino-5-oxo-1-phenylprolinate

: 1304774-15-9
methyl (2S,4S)-4-(4-methylbenzenesulfonyl)amino-1-phenylprolinate

: 1304774-17-1
(2S,4S)-2-hydroxymethyl-4-(4-methylbenzenesulfonyl)amino-1-phenylpyrrolidine

Guidance literature:: With dimethylsulfide borane complex; In tetrahydrofuran; at -5 - 0 ℃; for 72.5h; chemoselective reaction; Inert atmosphere;
DOI:10.1002/ejoc.201100049

Reference yield: 43.0%

: 1304774-14-8
tert-butyl (2S,4S)-4-(4-methylbenzenesulfonyl)amino-5-oxo-1-phenylprolinate

: 1304774-20-6
(2S,4S)-4-(4-methylbenzenesulfonyl)amino-1-phenylpyrrolidine-2-carbaldehyde

: 1304774-17-1
(2S,4S)-2-hydroxymethyl-4-(4-methylbenzenesulfonyl)amino-1-phenylpyrrolidine

: 1304774-16-0
tert-butyl (2S,4S)-4-(4-methylbenzenesulfonyl)amino-1-phenylprolinate

Guidance literature:: With dimethylsulfide borane complex; In tetrahydrofuran; at -5 - 0 ℃; for 168.5h; chemoselective reaction; Inert atmosphere;
DOI:10.1002/ejoc.201100049