tert-butyldiphenyl[(1R)-1-phenethyl-3-(tetrahydro-2H-2-pyranyloxy)propyl]oxysilane

Base Information

Chemical Name:tert-butyldiphenyl[(1R)-1-phenethyl-3-(tetrahydro-2H-2-pyranyloxy)propyl]oxysilane
CAS No.:936716-26-6
Molecular Formula:C₃₂H₄₂O₃Si
Molecular Weight:502.769
Hs Code.:

Synonyms:tert-butyldiphenyl[(1R)-1-phenethyl-3-(tetrahydro-2H-2-pyranyloxy)propyl]oxysilane

Suppliers and Price of tert-butyldiphenyl[(1R)-1-phenethyl-3-(tetrahydro-2H-2-pyranyloxy)propyl]oxysilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyldiphenyl[(1R)-1-phenethyl-3-(tetrahydro-2H-2-pyranyloxy)propyl]oxysilane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyldiphenyl[(1R)-1-phenethyl-3-(tetrahydro-2H-2-pyranyloxy)propyl]oxysilane

There total 4 articles about tert-butyldiphenyl[(1R)-1-phenethyl-3-(tetrahydro-2H-2-pyranyloxy)propyl]oxysilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 936716-25-5
(3R)-1-phenyl-5-(tetrahydro-2H-2-pyranyloxy)pentan-3-ol

: 58479-61-1
tert-butylchlorodiphenylsilane

: 936716-26-6
tert-butyldiphenyl[(1R)-1-phenethyl-3-(tetrahydro-2H-2-pyranyloxy)propyl]oxysilane

Guidance literature:: With 1H-imidazole; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1055/s-2007-965904

Reference yield:

: C₁₀H₁₆O₃

: 936716-26-6
tert-butyldiphenyl[(1R)-1-phenethyl-3-(tetrahydro-2H-2-pyranyloxy)propyl]oxysilane

Guidance literature:: Multi-step reaction with 3 steps

1.1: CuI; Ph₃P; potassium carbonate / Pd/C / 1,2-dimethoxy-ethane; H₂O / 0.5 h / 20 °C

1.2: 90 percent / 1,2-dimethoxy-ethane; H₂O / 2 h / 80 °C

2.1: 90 percent / H₂ / Pd/C / ethyl acetate / 6 h / 20 °C

3.1: 95 percent / imidazole / CH₂Cl₂ / 2 h / 0 °C

With 1H-imidazole; copper(l) iodide; hydrogen; potassium carbonate; triphenylphosphine; palladium on activated charcoal; In 1,2-dimethoxyethane; dichloromethane; water; ethyl acetate;
DOI:10.1055/s-2007-965904

Reference yield:

: 936716-24-4
(3S)-1-phenyl-5-(tetrahydro-2H-2-pyranyloxy)pent-1-yn-3-ol

: 936716-26-6
tert-butyldiphenyl[(1R)-1-phenethyl-3-(tetrahydro-2H-2-pyranyloxy)propyl]oxysilane

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / H₂ / Pd/C / ethyl acetate / 6 h / 20 °C

2: 95 percent / imidazole / CH₂Cl₂ / 2 h / 0 °C

With 1H-imidazole; hydrogen; palladium on activated charcoal; In dichloromethane; ethyl acetate;
DOI:10.1055/s-2007-965904