2'-hydroxy-α,4',6'-trimethoxychalcone

Base Information

• Chemical Name: 2'-hydroxy-α,4',6'-trimethoxychalcone
• CAS No.: 109469-62-7
• Molecular Formula: C₁₈H₁₈O₅
• Molecular Weight: 314.338
• Mol file: 109469-62-7.mol

Synonyms:2'-hydroxy-α,4',6'-trimethoxychalcone

Chemical Property of 2'-hydroxy-α,4',6'-trimethoxychalcone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2'-hydroxy-α,4',6'-trimethoxychalcone

There total 4 articles about 2'-hydroxy-α,4',6'-trimethoxychalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2'-hydroxy-2,4',6'-trimethoxyacetophenone (17874-42-9) + benzaldehyde (100-52-7) → 2'-hydroxy-α,4',6'-trimethoxy-chalcone (109469-62-7)

Guidance literature:

With sodium hydroxide; ethanol;

Reference yield:

2'-hydroxy-2,4',6'-trimethoxyacetophenone (17874-42-9) + benzaldehyde (100-52-7) → 2'-hydroxy-α,4',6'-trimethoxychalcone (109469-62-7)

Guidance literature:

With sodium hydroxide;

DOI:10.1016/0040-4020(96)00334-1

Reference yield:

3,5,7-trimethoxyflavone (26964-29-4) → 2'-hydroxy-α,4',6'-trimethoxy-chalcone (109469-62-7)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanolic KOH

2: ethanol; aq. NaOH solution

With potassium hydroxide; sodium hydroxide; ethanol;

upstream raw materials:

2'-hydroxy-2,4',6'-trimethoxyacetophenone

benzaldehyde

3,5,7-trimethoxyflavone

Downstream raw materials:

(αRS,βSR)-2-(α-hydroxybenzyl)-2,4,6-trimethoxybenzofuran-3(2H)-one

2-benzyl-2,4,6-trimethoxy-benzofuran-3-one

3,5,7-trimethoxyflavone

3-benzylidene-4,6-dimethoxybenzofuran-2(3H)-one