4-methylbenzenesulfonic acid 3-[(anthracen-9-ylmethyl)(tert-butoxycarbonyl)amino]propyl ester

Base Information

• Chemical Name: 4-methylbenzenesulfonic acid 3-[(anthracen-9-ylmethyl)(tert-butoxycarbonyl)amino]propyl ester
• CAS No.: 561300-94-5
• Molecular Formula: C₃₀H₃₃NO₅S
• Molecular Weight: 519.662
• Mol file: 561300-94-5.mol

Synonyms:4-methylbenzenesulfonic acid 3-[(anthracen-9-ylmethyl)(tert-butoxycarbonyl)amino]propyl ester

Chemical Property of 4-methylbenzenesulfonic acid 3-[(anthracen-9-ylmethyl)(tert-butoxycarbonyl)amino]propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methylbenzenesulfonic acid 3-[(anthracen-9-ylmethyl)(tert-butoxycarbonyl)amino]propyl ester

There total 5 articles about 4-methylbenzenesulfonic acid 3-[(anthracen-9-ylmethyl)(tert-butoxycarbonyl)amino]propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

p-toluenesulfonyl chloride (98-59-9) + (anthracen-9-ylmethyl)(3-hydroxypropyl)carbamic acid tert-butyl ester (561300-91-2) → 4-methylbenzenesulfonic acid 3-[(anthracen-9-ylmethyl)(tert-butoxycarbonyl)amino]propyl ester (561300-94-5)

Guidance literature:

With pyridine; at 0 - 5 ℃;

DOI:10.1021/jm030028w

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → 4-methylbenzenesulfonic acid 3-[(anthracen-9-ylmethyl)(tert-butoxycarbonyl)amino]propyl ester (561300-94-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / pyridine / methanol / 0 - 20 °C

2: 51 percent / pyridine / 0 - 5 °C

With pyridine; In methanol;

DOI:10.1021/jm030028w

Reference yield:

3-[(anthracen-9-ylmethyl)-amino]-propan-1-ol (14131-13-6) → 4-methylbenzenesulfonic acid 3-[(anthracen-9-ylmethyl)(tert-butoxycarbonyl)amino]propyl ester (561300-94-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / pyridine / methanol / 0 - 20 °C

2: 51 percent / pyridine / 0 - 5 °C

With pyridine; In methanol;

DOI:10.1021/jm030028w

upstream raw materials:

p-toluenesulfonyl chloride

(anthracen-9-ylmethyl)(3-hydroxypropyl)carbamic acid tert-butyl ester

di-tert-butyl dicarbonate

3-[(anthracen-9-ylmethyl)-amino]-propan-1-ol

Downstream raw materials:

toluene-4-sulfonic acid 5-{[3-(anthracen-9-ylmethyl-tert-butoxycarbonyl-amino)-propyl]-tert-butoxycarbonyl-amino}-pentyl ester

toluene-4-sulfonic acid 4-{[3-(anthracen-9-ylmethyl-tert-butoxycarbonylamino)propyl]-tert-butoxycarbonylamino}butyl ester