1,1',2'-tris(diphenylphosphino)-4-tert-butylferrocene

Base Information

• Chemical Name: 1,1',2'-tris(diphenylphosphino)-4-tert-butylferrocene
• CAS No.: 878190-65-9
• Molecular Formula: C₅₀H₄₅FeP₃
• Molecular Weight: 794.676
• Mol file: 878190-65-9.mol

Synonyms:1,1',2'-tris(diphenylphosphino)-4-tert-butylferrocene

Chemical Property of 1,1',2'-tris(diphenylphosphino)-4-tert-butylferrocene

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of 1,1',2'-tris(diphenylphosphino)-4-tert-butylferrocene

There total 2 articles about 1,1',2'-tris(diphenylphosphino)-4-tert-butylferrocene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

lithium diphenylphosphinocyclopentadienyl (83272-80-4) + iron(II) chloride + 1,2-bis(diphenylphosphanyl)-4-tert-butylcyclopentadienyl lithium → 1,1'-bis-(diphenylphosphino)ferrocene (12150-46-8) + 1,1′,2,2′-tetrakis(diphenylphosphino)-4,4′-di-tert-butylferrocene (403815-19-0) + 1,1',2'-tris(diphenylphosphino)-4-tert-butylferrocene (878190-65-9)

Guidance literature:

In tetrahydrofuran; (Ar); dropwise addn. of a soln. of trisubstituted lithium compd. in THF to a suspn. of iron salt in THF at -40°C, stirring for 2 h at room temp., addn. of a soln. of monosubstituted lithium salt in THF at -40°C; evapn., reflux in toluene for 3 h, cooling, filtration, column chromy. (SiO2, toluene/hexane 4:1); elem. anal.;

DOI:10.1021/om050882g

Reference yield: 84.0%

lithium diphenylphosphinocyclopentadienyl (83272-80-4) + iron(II) chloride + 1,2-bis(diphenylphosphanyl)-4-tert-butylcyclopentadienyl lithium → 1,1',2'-tris(diphenylphosphino)-4-tert-butylferrocene (878190-65-9)

Guidance literature:

In tetrahydrofuran; (Ar); Schlenk technique; soln. of BuCp(PPh2)2Li in THF was added to stirred suspn. of FeCl2 in THF at -40°C; stirred for 2 h; treated with soln. of Cp(PPh2)Li in THF at -40°C; evapd. (vac.); refluxed in toluene for 3 h; filtered; chromd. (SiO2, toluene/hexane, 4/1); elem. anal.;

DOI:10.1021/ic7022105

Reference yield: 95.0%

1,1',2'-tris(diphenylphosphino)-4-tert-butylferrocene (878190-65-9) + palladium dichloride → [PdCl2(1,1',2-tris(diphenylphosphino)-4-tert-butylferrocene)] (1013935-17-5)

Guidance literature:

In tetrahydrofuran; (Ar); Schlenk technique; mixt. of Fe complex and PdCl2 in THF was refluxed under stirring overnight; evapd. (vac.); dissolved in CH2Cl2; ether added; filtered; evapd.; crystd. (CH2cl2/hexane); elem. anal.;

DOI:10.1021/ic7022105

upstream raw materials:

lithium diphenylphosphinocyclopentadienyl

Downstream raw materials:

[NiCl₂(1,1',2-tris(diphenylphosphino)-4-tert-butylferrocene)]

[PdCl₂(1,1',2-tris(diphenylphosphino)-4-tert-butylferrocene)]