3-salicylaminocoumarin

Base Information

• Chemical Name: 3-salicylaminocoumarin
• CAS No.: 97472-95-2
• Molecular Formula: C₁₆H₁₃NO₃
• Molecular Weight: 267.284
• Mol file: 97472-95-2.mol

Synonyms:3-salicylaminocoumarin

Chemical Property of 3-salicylaminocoumarin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-salicylaminocoumarin

There total 3 articles about 3-salicylaminocoumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

3-[(2-hydroxy-benzylidene)amino]chromen-2-one (1473-60-5,910217-51-5) → 3-salicylaminocoumarin (97472-95-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In 1,4-dioxane;

DOI:10.1002/jhet.5570230118

Reference yield:

salicylaldehyde (90-02-8) → 3-salicylaminocoumarin (97472-95-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / triethylamine / H₂O / 0.5 h / Ambient temperature; pH 9

2: 70 percent / H₂ / 10percent Pd/C / dioxane

With hydrogen; triethylamine; palladium on activated charcoal; In 1,4-dioxane; water;

DOI:10.1002/jhet.5570230118

Reference yield:

aminocoumarine (1635-31-0) → 3-salicylaminocoumarin (97472-95-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / triethylamine / H₂O / 0.5 h / Ambient temperature; pH 9

2: 70 percent / H₂ / 10percent Pd/C / dioxane

With hydrogen; triethylamine; palladium on activated charcoal; In 1,4-dioxane; water;

DOI:10.1002/jhet.5570230118

upstream raw materials:

3-[(2-hydroxy-benzylidene)amino]chromen-2-one

aminocoumarine

salicylaldehyde

Downstream raw materials:

2-hydroxy-phenylalanine

Refernces