N-(5-bromo-2-pyridinyl)-(2-(4-cyanophenylcarbonyl)amino)-5-fluorophenylcarboxamide

Base Information

Chemical Name:N-(5-bromo-2-pyridinyl)-(2-(4-cyanophenylcarbonyl)amino)-5-fluorophenylcarboxamide
CAS No.:330943-05-0
Molecular Formula:C₂₀H₁₂BrFN₄O₂
Molecular Weight:439.243
Hs Code.:

Synonyms:N-(5-bromo-2-pyridinyl)-(2-(4-cyanophenylcarbonyl)amino)-5-fluorophenylcarboxamide

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Chemical Property of N-(5-bromo-2-pyridinyl)-(2-(4-cyanophenylcarbonyl)amino)-5-fluorophenylcarboxamide

Chemical Property:

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Technology Process of N-(5-bromo-2-pyridinyl)-(2-(4-cyanophenylcarbonyl)amino)-5-fluorophenylcarboxamide

There total 4 articles about N-(5-bromo-2-pyridinyl)-(2-(4-cyanophenylcarbonyl)amino)-5-fluorophenylcarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 330943-03-8
N-(5-bromo-2-pyridinyl)-(2-amino)-5-fluorophenylcarboxamide

: 6068-72-0
4-cyanobenzoyl chlorIde

: 330943-05-0
N-(5-bromo-2-pyridinyl)-(2-(4-cyanophenylcarbonyl)amino)-5-fluorophenylcarboxamide

Guidance literature:: With pyridine; In dichloromethane;

Reference yield:

: 320-98-9
5-fluoro-2-nitrobenzoic acid

: 330943-05-0
N-(5-bromo-2-pyridinyl)-(2-(4-cyanophenylcarbonyl)amino)-5-fluorophenylcarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine; trichlorophosphate / 0.5 h

2: tin(II) chloride dihdyrate / ethyl acetate / 4 h / Reflux

3: pyridine / dichloromethane / 20 °C

With pyridine; tin(II) chloride dihdyrate; trichlorophosphate; In dichloromethane; ethyl acetate;

Reference yield:

: 330943-02-7
N-(5-bromo-2-pyridinyl)(2-nitro)-5-fluorophenylcarboxamide

: 330943-05-0
N-(5-bromo-2-pyridinyl)-(2-(4-cyanophenylcarbonyl)amino)-5-fluorophenylcarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: tin(II) chloride dihdyrate / ethyl acetate / 4 h / Reflux

2: pyridine / dichloromethane / 20 °C

With pyridine; tin(II) chloride dihdyrate; In dichloromethane; ethyl acetate;