5-amino-1-(2-phenylethyl)-4-[3-phenyl-1,2,4-triazolo-5-yl]pyrazole

Base Information

• Chemical Name: 5-amino-1-(2-phenylethyl)-4-[3-phenyl-1,2,4-triazolo-5-yl]pyrazole
• CAS No.: 512845-10-2
• Molecular Formula: C₁₉H₁₈N₆
• Molecular Weight: 330.392
• Mol file: 512845-10-2.mol

Synonyms:5-amino-1-(2-phenylethyl)-4-[3-phenyl-1,2,4-triazolo-5-yl]pyrazole

Chemical Property of 5-amino-1-(2-phenylethyl)-4-[3-phenyl-1,2,4-triazolo-5-yl]pyrazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 5-amino-1-(2-phenylethyl)-4-[3-phenyl-1,2,4-triazolo-5-yl]pyrazole

There total 5 articles about 5-amino-1-(2-phenylethyl)-4-[3-phenyl-1,2,4-triazolo-5-yl]pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-(2-phenylethyl)-2-phenylpyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine (512844-93-8) → 5-amino-1-(2-phenylethyl)-4-[3-phenyl-1,2,4-triazolo-5-yl]pyrazole (512845-10-2)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; for 0.75h; Heating;

DOI:10.1021/jm021023m

Reference yield:

benzoic acid hydrazide (613-94-5) → 5-amino-1-(2-phenylethyl)-4-[3-phenyl-1,2,4-triazolo-5-yl]pyrazole (512845-10-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 2-methoxy-ethanol / 12 h / Heating

2: diphenyl ether / 1.5 h / 260 °C

3: aq. HCl / dioxane / 0.75 h / Heating

With hydrogenchloride; In 1,4-dioxane; diphenylether; 2-methoxy-ethanol;

DOI:10.1021/jm021023m

Reference yield:

5-amino-4-cyano-1-(β-phenylethyl)pyrazole (159979-74-5) → 5-amino-1-(2-phenylethyl)-4-[3-phenyl-1,2,4-triazolo-5-yl]pyrazole (512845-10-2)

Guidance literature:

Multi-step reaction with 4 steps

1: Heating

2: 2-methoxy-ethanol / 12 h / Heating

3: diphenyl ether / 1.5 h / 260 °C

4: aq. HCl / dioxane / 0.75 h / Heating

With hydrogenchloride; In 1,4-dioxane; diphenylether; 2-methoxy-ethanol;

DOI:10.1021/jm021023m

upstream raw materials:

7-(2-phenylethyl)-2-phenylpyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine

benzoic acid hydrazide

5-amino-4-cyano-1-(β-phenylethyl)pyrazole

N-(4-cyano-2-phenethyl-2H-pyrazol-3-yl)-formimidic acid ethyl ester