6-Methylpyrazine-2-carbohydrazide

Base Information

Chemical Name:6-Methylpyrazine-2-carbohydrazide
CAS No.:105426-65-1
Molecular Formula:C₆H₈N₄O
Molecular Weight:152.156
Hs Code.:
DSSTox Substance ID:DTXSID90544084
Wikidata:Q82421066
Mol file:105426-65-1.mol

Synonyms:6-Methylpyrazine-2-carbohydrazide;105426-65-1;Pyrazinecarboxylic acid, 6-methyl-, hydrazide (9CI);6-Methyl-2-pyrazinecarbohydrazide;SCHEMBL22518525;DTXSID90544084;AKOS006341633;6-methyl-2-Pyrazinecarboxylic acid hydrazide;A896008

Suppliers and Price of 6-Methylpyrazine-2-carbohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Methylpyrazine-2-carbohydrazide 97%
5g
$ 864.00

Chemenu
6-Methylpyrazine-2-carbohydrazide 95+%
5g
$ 808.00

Alichem
6-Methylpyrazine-2-carbohydrazide
1g
$ 400.00

Total 8 raw suppliers

Chemical Property of 6-Methylpyrazine-2-carbohydrazide

Chemical Property:

PSA：84.39000
LogP:0.66360
XLogP3:-0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:152.06981089
Heavy Atom Count:11
Complexity:150

Purity/Quality:

97% ^*data from raw suppliers

6-Methylpyrazine-2-carbohydrazide 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN=CC(=N1)C(=O)NN

Technology Process of 6-Methylpyrazine-2-carbohydrazide

There total 1 articles about 6-Methylpyrazine-2-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 41110-38-7
methyl 6-methylpyrazine-2-carboxylate

: 105426-65-1
6-methylpyrazine-2-carbohydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; at 20 ℃; for 14h; Inert atmosphere;
DOI:10.1021/jm5017413

Reference yield: 51.0%

: 1429560-52-0
(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine

: 105426-65-1
6-methylpyrazine-2-carbohydrazide

: (R)-7-(2,4-dimethoxybenzyl)-8-methyl-3-(6-methylpyrazin-2-yl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine

Guidance literature:: In methanol; at 60 - 70 ℃; for 8h; Inert atmosphere;
DOI:10.1021/jm5017413

Reference yield:

: 105426-65-1
6-methylpyrazine-2-carbohydrazide

: (R)-(8-methyl-3-(6-methylpyrazin-2-yl)-5,6-dihydro-[1,2,4]-triazolo[4,3-a]pyrazin-7(8H)-yl)(4-(thiophen-2-yl)phenyl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: methanol / 8 h / 60 - 70 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 0.25 h / 0 - 20 °C / Inert atmosphere

2.2: 0.5 h / Inert atmosphere

3.1: 4-methyl-morpholine / dichloromethane / 0.5 h / 0 - 20 °C / Inert atmosphere

3.2: 0.17 h / 0 - 20 °C / Inert atmosphere

With 4-methyl-morpholine; trifluoroacetic acid; In methanol; dichloromethane;
DOI:10.1021/jm5017413