2-(4-(cyclopropylmethoxy)-3-(morpholinomethyl)benzoyloxy)acetic acid

Base Information

Chemical Name:2-(4-(cyclopropylmethoxy)-3-(morpholinomethyl)benzoyloxy)acetic acid
CAS No.:1428847-89-5
Molecular Formula:C₁₈H₂₃NO₆
Molecular Weight:349.384
Hs Code.:

Synonyms:2-(4-(cyclopropylmethoxy)-3-(morpholinomethyl)benzoyloxy)acetic acid

Suppliers and Price of 2-(4-(cyclopropylmethoxy)-3-(morpholinomethyl)benzoyloxy)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-(cyclopropylmethoxy)-3-(morpholinomethyl)benzoyloxy)acetic acid

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-(4-(cyclopropylmethoxy)-3-(morpholinomethyl)benzoyloxy)acetic acid

There total 5 articles about 2-(4-(cyclopropylmethoxy)-3-(morpholinomethyl)benzoyloxy)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1428847-88-4
2-(benzyloxy)-2-oxoethyl 4-(cyclopropylmethoxy)-3-(morpholinomethyl)benzoate?

: 1428847-89-5
2-(4-(cyclopropylmethoxy)-3-(morpholinomethyl)benzoyloxy)acetic acid

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In methanol; for 1h; under 3102.97 Torr;

Reference yield:

: 24589-99-9
methyl 3-formyl-4-hydroxybenzoate

: 1428847-89-5
2-(4-(cyclopropylmethoxy)-3-(morpholinomethyl)benzoyloxy)acetic acid

Guidance literature:: Multi-step reaction with 5 steps

1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C

2: sodium hydroxide / methanol / 4 h / 40 °C

3: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C / Inert atmosphere

4: sodium tris(acetoxy)borohydride; acetic acid / tetrahydrofuran / 24 h / 20 °C / pH 5 - 6 / Inert atmosphere

5: 5%-palladium/activated carbon; hydrogen / methanol / 1 h / 3102.97 Torr

With dmap; 5%-palladium/activated carbon; hydrogen; sodium tris(acetoxy)borohydride; potassium carbonate; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1428847-86-2
methyl 4-(cyclopropylmethoxy)-3-formylbenzoate

: 1428847-89-5
2-(4-(cyclopropylmethoxy)-3-(morpholinomethyl)benzoyloxy)acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / methanol / 4 h / 40 °C

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C / Inert atmosphere

3: sodium tris(acetoxy)borohydride; acetic acid / tetrahydrofuran / 24 h / 20 °C / pH 5 - 6 / Inert atmosphere

4: 5%-palladium/activated carbon; hydrogen / methanol / 1 h / 3102.97 Torr

With dmap; 5%-palladium/activated carbon; hydrogen; sodium tris(acetoxy)borohydride; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane;