Pyrazinecarboxamide, 3-ethyl- (9CI)

Base Information

• Chemical Name: Pyrazinecarboxamide, 3-ethyl- (9CI)
• CAS No.: 104893-53-0
• Molecular Formula: C₇H₉N₃O
• Molecular Weight: 151.168
• Mol file: 104893-53-0.mol

Synonyms:Pyrazinecarboxamide,3-ethyl- (9CI)

Chemical Property of Pyrazinecarboxamide, 3-ethyl- (9CI)

Chemical Property:

• PSA: 68.87000
• LogP: 0.83820

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyrazinecarboxamide, 3-ethyl- (9CI)

There total 3 articles about Pyrazinecarboxamide, 3-ethyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-ethyl-pyrazine-2-carbonitrile (104893-58-5) → 3-ethyl-pyrazine-2-carboxylic acid amide (104893-53-0)

Guidance literature:

With sulfuric acid; at 125 ℃;

DOI:10.1021/ja01591a029

Reference yield:

3-ethyl-1H-pyrazin-2-one (25680-54-0) → 3-ethyl-pyrazine-2-carboxylic acid amide (104893-53-0)

Guidance literature:

Multi-step reaction with 3 steps

1: POBr₃

3: concentrated H₂SO₄ / 125 °C

With sulfuric acid; phosphorus(V) oxybromide;

DOI:10.1021/ja01591a029

Reference yield:

2-ethyl-3-bromo-pyrazine (859300-56-4) → 3-ethyl-pyrazine-2-carboxylic acid amide (104893-53-0)

Guidance literature:

Multi-step reaction with 2 steps

2: concentrated H₂SO₄ / 125 °C

With sulfuric acid;

DOI:10.1021/ja01591a029

upstream raw materials:

3-ethyl-pyrazine-2-carbonitrile

3-ethyl-1H-pyrazin-2-one

2-ethyl-3-bromo-pyrazine