tert-Butyl-dimethyl-(4-methylene-3-{2-[7a-methyl-1-(1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-ylidene]-ethylidene}-cyclohexyloxy)-silane

Base Information

Chemical Name:tert-Butyl-dimethyl-(4-methylene-3-{2-[7a-methyl-1-(1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-ylidene]-ethylidene}-cyclohexyloxy)-silane
CAS No.:104846-62-0
Molecular Formula:C34H58 O Si
Molecular Weight:510.919
Hs Code.:
Mol file:104846-62-0.mol

tert-Butyl-dimethyl-(4-methylene-3-{2-[7a-methyl-1-(1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-ylidene]-ethylidene}-cyclohexyloxy)-silane

Synonyms:Silane,(1,1-dimethylethyl)[[(3b,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-yl]oxy]dimethyl-(9CI)

Suppliers and Price of tert-Butyl-dimethyl-(4-methylene-3-{2-[7a-methyl-1-(1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-ylidene]-ethylidene}-cyclohexyloxy)-silane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
VitaminD2O-t-ButyldimethylsilylEther
25g
$ 610.00

Total 2 raw suppliers

Chemical Property of tert-Butyl-dimethyl-(4-methylene-3-{2-[7a-methyl-1-(1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-ylidene]-ethylidene}-cyclohexyloxy)-silane

Chemical Property:

Refractive Index:1.505
PSA：9.23000
LogP:10.67050

Purity/Quality:

99% ^*data from raw suppliers

VitaminD2O-t-ButyldimethylsilylEther ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Vitamin D2 O-t-Butyldimethylsilyl Ether is an impurity of Vitamin D2 (V676040), which is a synthetic form of Vitamin D. Prepared from ergosterol by UV irradiation in a suitable solvent. Commercial solutions are usually made with propylene glycol or sesame oil. Antirachitic.Vitamin D2 O-t-Butyldimethylsilyl Ether is also an intermediate in synthesizing (7Z)-Calcipotriene (C144225), which is an isomeric impurity of Calcipotriene (1442000), a vitamin D3 analogue with low calcemic activity.

Technology Process of tert-Butyl-dimethyl-(4-methylene-3-{2-[7a-methyl-1-(1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-ylidene]-ethylidene}-cyclohexyloxy)-silane

There total 13 articles about tert-Butyl-dimethyl-(4-methylene-3-{2-[7a-methyl-1-(1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-ylidene]-ethylidene}-cyclohexyloxy)-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 50-14-6
Calciferol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 104846-62-0
3(S)-tert-butyldimethylsilyloxy-9,10-secoergosta-5,7(E),10⁽¹⁹⁾,22(E)-tetraene

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; for 2.5h;
DOI:10.1021/jo00261a020

Reference yield: 94.0%

: 170081-43-3,251445-16-6
SO2-adduct of 3(S)-<(tert-butyldimethylsilyl)oxy>-9,10-secoergosta-5,7(E),10(19),22(E)-tetraene

: 104846-62-0,104846-63-1
(5E)-vitamin D₂ tert-butyldimethylsilyl ether

Guidance literature:: With sodium hydrogencarbonate; In ethanol; for 1.25h; Heating;
DOI:10.1021/jo00058a034

Reference yield:

: 50-14-6
Calciferol

: 104846-62-0,104846-63-1
(5E)-vitamin D₂ tert-butyldimethylsilyl ether

Guidance literature:: Multi-step reaction with 3 steps

1: SO₂ / CH₂Cl₂ / 1.25 h / -10 °C

2: imidazole / Ambient temperature

3: 94 percent / NaHCO₃ / aq. ethanol / 1.25 h / Heating

With 1H-imidazole; sulfur dioxide; sodium hydrogencarbonate; In ethanol; dichloromethane;
DOI:10.1021/jo00058a034