N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid

Base Information

• Chemical Name: N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid
• CAS No.: 69038-04-6
• Molecular Formula: C₁₃H₂₀N₂O₆
• Molecular Weight: 300.312

Synonyms:N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid

Chemical Property of N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
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MSDS Files:

SDS file from LookChem

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Technology Process of N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid

There total 1 articles about N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di(succinimido) carbonate (74124-79-1) + N-tert-butoxycarbonyl-3-aminopropanol (58885-58-8) → N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid (69038-04-6)

Guidance literature:

With triethylamine; In acetonitrile;

DOI:10.1016/j.tetlet.2007.07.147

Reference yield: 61.0%

N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid (69038-04-6) → 4-amino-1-hydroxybutylidenebisphosphonic acid (66376-36-1)

Guidance literature:

With tris(trimethylsilyl) phosphite; In tetrahydrofuran; at 50 ℃; for 72h;

DOI:10.1002/ejoc.200601067

Reference yield:

2-(4-amino-phenylamino)-1,4-naphthoquinone (858020-17-4) + N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid (69038-04-6) → C25H27N3O5

Guidance literature:

With dmap; In 1,4-dioxane; at 80 ℃; for 24h;

DOI:10.1371/journal.pone.0107994

upstream raw materials:

di(succinimido) carbonate

N-tert-butoxycarbonyl-3-aminopropanol

Downstream raw materials:

N^γ-tert-butoxycarbonylbutyryl-β-benzyl-L-asparaginic acid α-amide

N^γ-tert-butoxycarbonylaminobutyryl-L-tryptophyl-L-leucyl-β-benzyl-L-asparaginic acid α-amide

4-amino-1-hydroxybutylidenebisphosphonic acid

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