5-chloro-α-fluoro-2-methoxy-α-[2-nitro-4-(trifluoromethyl)-phenyl]benzeneacetic acid,methyl ester

Base Information

Chemical Name:5-chloro-α-fluoro-2-methoxy-α-[2-nitro-4-(trifluoromethyl)-phenyl]benzeneacetic acid,methyl ester
CAS No.:206194-00-5
Molecular Formula:C₁₇H₁₂ClF₄NO₅
Molecular Weight:421.733
Hs Code.:

Synonyms:5-chloro-α-fluoro-2-methoxy-α-[2-nitro-4-(trifluoromethyl)-phenyl]benzeneacetic acid,methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-chloro-α-fluoro-2-methoxy-α-[2-nitro-4-(trifluoromethyl)-phenyl]benzeneacetic acid,methyl ester

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Technology Process of 5-chloro-α-fluoro-2-methoxy-α-[2-nitro-4-(trifluoromethyl)-phenyl]benzeneacetic acid,methyl ester

There total 2 articles about 5-chloro-α-fluoro-2-methoxy-α-[2-nitro-4-(trifluoromethyl)-phenyl]benzeneacetic acid,methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.3%

: 206194-00-5
5-chloro-α-fluoro-2-methoxy-α-[2-nitro-4-(trifluoromethyl)-phenyl]benzeneacetic acid,methyl ester

Guidance literature:

Reference yield: 80.0%

: 367-86-2
1-fluoro-2-nitro-4-trifluoromethyl-benzene

: 26939-01-5
5-chloro-2-methoxyphenylacetic acid,methyl ester

: 206194-00-5
5-chloro-α-fluoro-2-methoxy-α-[2-nitro-4-(trifluoromethyl)-phenyl]benzeneacetic acid,methyl ester

Guidance literature:: 5-chloro-2-methoxyphenylacetic acid,methyl ester; With potassium hexamethylsilazane; In tetrahydrofuran; at -78 ℃;

1-fluoro-2-nitro-4-trifluoromethyl-benzene; In tetrahydrofuran; at -78 - -40 ℃;

With N-fluorobis(benzenesulfon)imide; In tetrahydrofuran;
DOI:10.1016/S0960-894X(02)00101-4