1-AMINO-2-HYDROXY-NAPHTALENE-3-CARBOXYLIC ACID METHYL ESTER

Base Information

• Chemical Name: 1-AMINO-2-HYDROXY-NAPHTALENE-3-CARBOXYLIC ACID METHYL ESTER
• CAS No.: 104655-33-6
• Molecular Formula: C₁₂H₁₁NO₃
• Molecular Weight: 217.224
• Hs Code.: 2922509090
• Mol file: 104655-33-6.mol

Synonyms:1-AMINO-2-HYDROXY-NAPHTALENE-3-CARBOXYLIC ACID METHYL ESTER;METHYL 1-AMINO-2-HYDROXYNAPHTHALEN-3-CARBOXYLATE

Chemical Property of 1-AMINO-2-HYDROXY-NAPHTALENE-3-CARBOXYLIC ACID METHYL ESTER

Chemical Property:

• PSA: 72.55000
• LogP: 2.49540

Purity/Quality:

95% ^*data from raw suppliers

Methyl4-amino-3-hydroxy-2-naphthoate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-AMINO-2-HYDROXY-NAPHTALENE-3-CARBOXYLIC ACID METHYL ESTER

There total 4 articles about 1-AMINO-2-HYDROXY-NAPHTALENE-3-CARBOXYLIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

methyl 3-hydroxy-4-nitro-2-naphthoate (5394-81-0) → 1-amino-2-hydroxy-3-naphthoic acid methyl ester (104655-33-6)

Guidance literature:

With iron; ammonium chloride; In methanol; water; for 4h; Reflux;

DOI:10.2174/1570178611310050014

Reference yield:

3-hydroxy-2-naphthoic acid methyl ester (883-99-8) → 1-amino-2-hydroxy-3-naphthoic acid methyl ester (104655-33-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid; nitric acid / dichloromethane / 0.25 h / 0 °C

2: ammonium chloride; iron / methanol; water / 4 h / Reflux

With sulfuric acid; nitric acid; iron; ammonium chloride; In methanol; dichloromethane; water;

DOI:10.2174/1570178611310050014

Reference yield:

methyl 3-(trifluoromethanesulfonyloxy)naphthalene-2-carboxylate (288402-18-6) → 1-amino-2-hydroxy-3-naphthoic acid methyl ester (104655-33-6)

Guidance literature:

Multi-step reaction with 3 steps

1: palladium diacetate; caesium carbonate; CyJohnPhos / toluene / 100 °C

2: sulfuric acid; nitric acid / dichloromethane / 0.25 h / 0 °C

3: ammonium chloride; iron / methanol; water / 4 h / Reflux

With sulfuric acid; nitric acid; palladium diacetate; iron; ammonium chloride; caesium carbonate; CyJohnPhos; In methanol; dichloromethane; water; toluene;

DOI:10.2174/1570178611310050014

upstream raw materials:

methyl 3-hydroxy-4-nitro-2-naphthoate

3-hydroxy-2-naphthoic acid methyl ester

methyl 3-(trifluoromethanesulfonyloxy)naphthalene-2-carboxylate

Downstream raw materials:

2-(1-Formyl-2-phenyl-ethyl)-naphtho[1,2-d]oxazole-4-carboxylic acid methyl ester

3-Hydroxy-4-(3-phenyl-propionylamino)-naphthalene-2-carboxylic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 104655-33-6 1-AMINO-2-HYDROXY-NAPHTALENE-3-CARBOXYLIC ACID METHYL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send