N-{2-[3-endo-(3-carbamoyl-2-hydroxy-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-N-(2-ethyl-butyl)-succinamic acid trifluoroacetate

Base Information

Chemical Name:N-{2-[3-endo-(3-carbamoyl-2-hydroxy-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-N-(2-ethyl-butyl)-succinamic acid trifluoroacetate
CAS No.:1123662-36-1
Molecular Formula:C₂HF₃O₂*C₂₆H₃₉N₃O₅
Molecular Weight:587.637
Hs Code.:

Synonyms:N-{2-[3-endo-(3-carbamoyl-2-hydroxy-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-N-(2-ethyl-butyl)-succinamic acid trifluoroacetate

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Chemical Property of N-{2-[3-endo-(3-carbamoyl-2-hydroxy-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-N-(2-ethyl-butyl)-succinamic acid trifluoroacetate

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Technology Process of N-{2-[3-endo-(3-carbamoyl-2-hydroxy-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-N-(2-ethyl-butyl)-succinamic acid trifluoroacetate

There total 1 articles about N-{2-[3-endo-(3-carbamoyl-2-hydroxy-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-N-(2-ethyl-butyl)-succinamic acid trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-30-5
succinic acid anhydride

: 1123661-20-0
3-endo-(8-[2-(2-ethylbutylamino)ethyl]-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide

: 76-05-1
trifluoroacetic acid

: 1123662-36-1
N-{2-[3-endo-(3-carbamoyl-2-hydroxy-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-N-(2-ethyl-butyl)-succinamic acid trifluoroacetate

Guidance literature:: succinic acid anhydride; 3-endo-(8-[2-(2-ethylbutylamino)ethyl]-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

With acetic acid; In water;

trifluoroacetic acid;