7-Chloro-1-phenyl-3,4-dihydroisoquinoline

Base Information

Chemical Name:7-Chloro-1-phenyl-3,4-dihydroisoquinoline
CAS No.:104576-30-9
Molecular Formula:C15H12 Cl N
Molecular Weight:241.72
Hs Code.:2933499090
ChEMBL ID:CHEMBL3303728
DSSTox Substance ID:DTXSID60470048
Nikkaji Number:J3.534.327J
Mol file:104576-30-9.mol

Synonyms:104576-30-9;7-chloro-1-phenyl-3,4-dihydroisoquinoline;7-CHLORO-1-PHENYL-3,4-DIHYDRO-ISOQUINOLINE;Isoquinoline,7-chloro-3,4-dihydro-1-phenyl-;CHEMBL3303728;DTXSID60470048;AKOS015965407

Suppliers and Price of 7-Chloro-1-phenyl-3,4-dihydroisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 7-Chloro-1-phenyl-3,4-dihydroisoquinoline

Chemical Property:

PSA：12.36000
LogP:3.16910
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:241.0658271
Heavy Atom Count:17
Complexity:293

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3

Technology Process of 7-Chloro-1-phenyl-3,4-dihydroisoquinoline

There total 12 articles about 7-Chloro-1-phenyl-3,4-dihydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 104576-30-9
1-phenyl-7-chloro-3,4-dihydroisoquinoline

Guidance literature:: With trichlorophosphate; In 5,5-dimethyl-1,3-cyclohexadiene; for 2h; Reflux;

Reference yield: 76.0%

: 741615-46-3
7-chloro-1-phenyl-1,2,3,4-tetrahydroisoquinoline

: 104576-30-9
1-phenyl-7-chloro-3,4-dihydroisoquinoline

: C₁₅H₁₀ClN

Guidance literature:: With potassium phosphate tribasic trihydrate; 5%-palladium/activated carbon; oxygen; In acetonitrile; at 60 ℃; chemoselective reaction; Green chemistry;
DOI:10.1016/S1872-2067(14)60243-6

Reference yield: 75.0%

: 741615-46-3
7-chloro-1-phenyl-1,2,3,4-tetrahydroisoquinoline

: 104576-30-9
1-phenyl-7-chloro-3,4-dihydroisoquinoline

Guidance literature:: With N,N-dimethyl-formamide; at 100 ℃; for 24h; chemoselective reaction; Schlenk technique; Green chemistry;
DOI:10.1016/j.tetlet.2016.01.008