4-fluoro-N-(2,2,2-trifluoro-1-phenylethylidene)-L-leucine potassium salt

Base Information

Chemical Name:4-fluoro-N-(2,2,2-trifluoro-1-phenylethylidene)-L-leucine potassium salt
CAS No.:1056162-23-2
Molecular Formula:C₁₄H₁₄F₄NO₂*K
Molecular Weight:343.363
Hs Code.:

Synonyms:4-fluoro-N-(2,2,2-trifluoro-1-phenylethylidene)-L-leucine potassium salt

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Chemical Property of 4-fluoro-N-(2,2,2-trifluoro-1-phenylethylidene)-L-leucine potassium salt

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Technology Process of 4-fluoro-N-(2,2,2-trifluoro-1-phenylethylidene)-L-leucine potassium salt

There total 1 articles about 4-fluoro-N-(2,2,2-trifluoro-1-phenylethylidene)-L-leucine potassium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 434-45-7
2,2,2-Trifluoroacetophenone

: 156047-39-1,885498-60-2
ethyl (2S)-2-amino-4-fluoro-4-methylpentanoate

: 1056162-23-2
4-fluoro-N-(2,2,2-trifluoro-1-phenylethylidene)-L-leucine potassium salt

Guidance literature:: With methanol; potassium carbonate; at 50 ℃; for 18h;

Reference yield:

: 1056162-23-2
4-fluoro-N-(2,2,2-trifluoro-1-phenylethylidene)-L-leucine potassium salt

: 4-fluoro-N-[(1R)-2,2,2-trifluoro-1-phenethyl]-L-leucine

: 4-fluoro-N-[(1S)-2,2,2-trifluoro-1-phenethyl]-L-leucine

Guidance literature:: 4-fluoro-N-(2,2,2-trifluoro-1-phenylethylidene)-L-leucine potassium salt; With sodium tetrahydroborate; water; In tetrahydrofuran; at 20 - 25 ℃; for 1 - 2h;

With sodium hydroxide; In tetrahydrofuran; water; Product distribution / selectivity;