(S)-ethyl 2-aMino-4-fluoro-4-Methylpentanoate

Base Information

Chemical Name:(S)-ethyl 2-aMino-4-fluoro-4-Methylpentanoate
CAS No.:156047-39-1
Molecular Formula:C8H16FNO2
Molecular Weight:177.21700
Hs Code.:
Mol file:156047-39-1.mol

Synonyms:ethyl (2S)-2-amino-4-fluoro-4-methylpentanoate;Ethyl (S)-2-amino-4-fluoro-4-methylpentanoate;(S)-ETHYL 2-AMINO-4-FLUORO-4-METHYLPENTANOATE HCL;L-4-fluoro-leucine ethyl ester;ethyl (2S)-2-amino-4-fluoro-4-methylpentanoate,hydrochloride;

Suppliers and Price of (S)-ethyl 2-aMino-4-fluoro-4-Methylpentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-Ethyl2-amino-4-fluoro-4-methylpentanoate
5mg
$ 90.00

TRC
(S)-Ethyl2-amino-4-fluoro-4-methylpentanoate
25mg
$ 310.00

ChemScene
(S)-ethyl2-amino-4-fluoro-4-methylpentanoate
250mg
$ 1050.00

ChemScene
(S)-ethyl2-amino-4-fluoro-4-methylpentanoate
100mg
$ 610.00

ChemScene
(S)-ethyl2-amino-4-fluoro-4-methylpentanoate
1g
$ 2100.00

Chemenu
ethyl(S)-2-amino-4-fluoro-4-methylpentanoate 95%
1g
$ 1386.00

Ambeed
(S)-Ethyl2-amino-4-fluoro-4-methylpentanoate 98%
100mg
$ 232.00

Ambeed
(S)-Ethyl2-amino-4-fluoro-4-methylpentanoate 98%
50mg
$ 166.00

Ambeed
(S)-Ethyl2-amino-4-fluoro-4-methylpentanoate 98%
25mg
$ 124.00

Ambeed
(S)-Ethyl2-amino-4-fluoro-4-methylpentanoate 98%
250mg
$ 347.00

Total 32 raw suppliers

Chemical Property of (S)-ethyl 2-aMino-4-fluoro-4-Methylpentanoate

Chemical Property:

Boiling Point:200.2±25.0 °C(Predicted)
PKA:6.44±0.48(Predicted)
PSA：52.32000
Density:1.020±0.06 g/cm3(Predicted)
LogP:1.71530

Purity/Quality:

97% ^*data from raw suppliers

(S)-Ethyl2-amino-4-fluoro-4-methylpentanoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-ethyl 2-aMino-4-fluoro-4-Methylpentanoate

There total 10 articles about (S)-ethyl 2-aMino-4-fluoro-4-Methylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: (S)-ethyl 2-amino-4-methylpent-4-enoate (+)-camphorsulfonic acid salt

: 156047-39-1,885498-60-2
ethyl (2S)-2-amino-4-fluoro-4-methylpentanoate

Guidance literature:: (S)-ethyl 2-amino-4-methylpent-4-enoate (+)-camphorsulfonic acid salt; With urea hydrogen fluoride; In water; at 0 - 20 ℃; for 3h; Inert atmosphere;

With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; trifluoroacetic acid; In tert-butyl methyl ether; water; at 0 - 20 ℃; for 4h; Inert atmosphere;

Reference yield:

: ethyl 2-(benzylamino)-4-fluoro-4-methylpentanoate

: 885498-60-2
ethyl (2R)-2-amino-4-fluoro-4-methylpentanoate

: 156047-39-1,885498-60-2
ethyl (2S)-2-amino-4-fluoro-4-methylpentanoate

Guidance literature:: With hydrogen; palladium dihydroxide; In ethanol; at 20 ℃; for 16h; under 2792.6 Torr; Title compound not separated from byproducts;
DOI:10.1055/s-2005-923593

Reference yield:

: 2743-40-0
L-leucine ethyl ester hydrochloride

: 156047-39-1,885498-60-2
ethyl (2S)-2-amino-4-fluoro-4-methylpentanoate

Guidance literature:: With tetrakis(tetrabutylammonium)decatungstate(VI); N-fluorobis(benzenesulfon)imide; In water; acetonitrile; for 66h; Solvent; Concentration; Time; Inert atmosphere; Sealed tube; UV-irradiation;