(4S,7R,8aR)-4,7-dibenzyl-7-methoxycarbonyl-3,6-dioxoperhydropyrrolo<1,2-a>pyrazine

Base Information

Chemical Name:(4S,7R,8aR)-4,7-dibenzyl-7-methoxycarbonyl-3,6-dioxoperhydropyrrolo<1,2-a>pyrazine
CAS No.:141996-78-3
Molecular Formula:C₂₃H₂₄N₂O₄
Molecular Weight:392.455
Hs Code.:

Synonyms:(4S,7R,8aR)-4,7-dibenzyl-7-methoxycarbonyl-3,6-dioxoperhydropyrrolo<1,2-a>pyrazine

Suppliers and Price of (4S,7R,8aR)-4,7-dibenzyl-7-methoxycarbonyl-3,6-dioxoperhydropyrrolo<1,2-a>pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,7R,8aR)-4,7-dibenzyl-7-methoxycarbonyl-3,6-dioxoperhydropyrrolo<1,2-a>pyrazine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,7R,8aR)-4,7-dibenzyl-7-methoxycarbonyl-3,6-dioxoperhydropyrrolo<1,2-a>pyrazine

There total 4 articles about (4S,7R,8aR)-4,7-dibenzyl-7-methoxycarbonyl-3,6-dioxoperhydropyrrolo<1,2-a>pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

: 184847-36-7
(4S,7R,8aR)-4,7-Dibenzyl-6-oxo-3-thioxo-octahydro-pyrrolo[1,2-a]pyrazine-7-carboxylic acid methyl ester

: 141996-78-3
(4S,7R,8aR)-4,7-dibenzyl-7-methoxycarbonyl-3,6-dioxoperhydropyrrolo<1,2-a>pyrazine

: (4R,7R,8aR)-4,7-Dibenzyl-3,6-dioxo-octahydro-pyrrolo[1,2-a]pyrazine-7-carboxylic acid methyl ester

Guidance literature:: With sodium tetrahydroborate; nickel dichloride; In tetrahydrofuran; methanol; for 0.5h; Ambient temperature;
DOI:10.1016/0040-4020(96)00842-3

Reference yield:

: 141996-73-8
2-[3-((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-2-oxo-propyl]-malonic acid dimethyl ester

: 141996-78-3
(4S,7R,8aR)-4,7-dibenzyl-7-methoxycarbonyl-3,6-dioxoperhydropyrrolo<1,2-a>pyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / H₂ / 10percent Pd/C / methanol / 120 h / 1551.4 Torr / Ambient temperature

2: 49 percent / NaOMe

With hydrogen; sodium methylate; palladium on activated charcoal; In methanol;
DOI:10.1016/0040-4039(92)88173-3

Reference yield:

: 141996-76-1
2-((2R,6S)-6-Benzyl-5-oxo-piperazin-2-ylmethyl)-malonic acid dimethyl ester

: 141996-78-3
(4S,7R,8aR)-4,7-dibenzyl-7-methoxycarbonyl-3,6-dioxoperhydropyrrolo<1,2-a>pyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / Heating

2: 49 percent / NaOMe

With sodium methylate; In toluene;
DOI:10.1016/0040-4039(92)88173-3