4-Trifluoromethylnicotinoyl chloride

Base Information

Chemical Name:4-Trifluoromethylnicotinoyl chloride
CAS No.:104326-73-0
Molecular Formula:C7H3 Cl F3 N O
Molecular Weight:209.555
Hs Code.:2933399090
DSSTox Substance ID:DTXSID30472852
Wikidata:Q82302034
Mol file:104326-73-0.mol

Synonyms:104326-73-0;4-trifluoromethylnicotinoyl chloride;4-(Trifluoromethyl)nicotinoyl chloride;4-(trifluoromethyl)pyridine-3-carbonyl Chloride;3-Pyridinecarbonyl chloride, 4-(trifluoromethyl)- (9CI);SCHEMBL2008577;DTXSID30472852;4-(Trifluoromethyl)nicotinoylchloride;4-trifluoromethyl-nicotinoyl chloride;4-trifluoromethylnicotinic acid chloride

Suppliers and Price of 4-Trifluoromethylnicotinoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Atlantic Research Chemicals
4-(Trifluoromethyl)nicotinoylchloride 95%
250mgs:
$ 151.99

Total 3 raw suppliers

Chemical Property of 4-Trifluoromethylnicotinoyl chloride

Chemical Property:

PSA：29.96000
LogP:2.47940
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:208.9855259
Heavy Atom Count:13
Complexity:206

Purity/Quality:

99%, ^*data from raw suppliers

4-(Trifluoromethyl)nicotinoylchloride 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=CC(=C1C(F)(F)F)C(=O)Cl

Technology Process of 4-Trifluoromethylnicotinoyl chloride

There total 3 articles about 4-Trifluoromethylnicotinoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.1%

: 158063-66-2
4-(trifluoromethyl)nicotinic acid

: 104326-73-0
4-(trifluoromethyl)pyridine-3-carbonyl chloride

Guidance literature:: With thionyl chloride; N,N-dimethyl-formamide; In benzene; for 3h; Heating / reflux;

Reference yield:

: 131747-43-8
2-(trifluoromethyl)nicotinic acid

: 104326-73-0
4-(trifluoromethyl)pyridine-3-carbonyl chloride

Guidance literature:: With thionyl chloride;

Reference yield:

: methyl 3-((4,4,4-trifluoro-3-oxobut-en-1-yl)amino)prop-2-enoate

: 104326-73-0
4-(trifluoromethyl)pyridine-3-carbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: sodium methylate / methanol / 6.5 h / 20 °C / Reflux

2: thionyl chloride; N,N-dimethyl-formamide / benzene / 3.5 h

With thionyl chloride; sodium methylate; N,N-dimethyl-formamide; In methanol; benzene;