N-((1-(3-aminopropyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide

Base Information

• Chemical Name: N-((1-(3-aminopropyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide
• CAS No.: 1224434-33-6
• Molecular Formula: C₁₄H₁₆F₃N₇O
• Molecular Weight: 355.323
• Mol file: 1224434-33-6.mol

Synonyms:N-((1-(3-aminopropyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide

Chemical Property of N-((1-(3-aminopropyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-((1-(3-aminopropyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide

There total 2 articles about N-((1-(3-aminopropyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

3-azidopropylamine (88192-19-2) + N-(prop-2-ynyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide (1224434-04-1) → N-((1-(3-aminopropyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide (1224434-33-6)

Guidance literature:

With copper(ll) sulfate pentahydrate; In methanol; water; at 20 ℃; for 0.0833333h; regioselective reaction; Inert atmosphere;

DOI:10.1016/j.tet.2010.02.042

Reference yield:

1-amino-2-azidoethane (87156-40-9) + 3-azidopropylamine (88192-19-2) + N-(prop-2-ynyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide (1224434-04-1) + 4-azidobutan-1-amine (88192-20-5) + 1-azido-5-aminopentane (148759-41-5) → N-((1-(2-aminoethyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide (1224434-30-3) + N-((1-(3-aminopropyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide (1224434-33-6) + N-((1-(4-aminobutyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide (1224434-34-7) + N-((1-(5-aminopentyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide (1224434-35-8)

Guidance literature:

With copper(ll) sulfate pentahydrate; In methanol; water; at 20 ℃; for 0.166667h; regioselective reaction; Inert atmosphere;

DOI:10.1016/j.tet.2010.02.042

upstream raw materials:

1-amino-2-azidoethane

3-azidopropylamine

N-(prop-2-ynyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide

4-azidobutan-1-amine