4-Azidobutan-1-amine

Base Information

• Chemical Name: 4-Azidobutan-1-amine
• CAS No.: 88192-20-5
• Molecular Formula: C4H10N4
• Molecular Weight: 114.15
• Hs Code.: 2929909090
• DSSTox Substance ID: DTXSID40236881
• Nikkaji Number: J541.505E
• Wikidata: Q83118978
• Mol file: 88192-20-5.mol

Synonyms:4-azidobutan-1-amine;88192-20-5;4-Azido-1-butanamine;4-azidobutylamine;1-Butanamine, 4-azido-;1-Butamine 4-azide;C4H10N4;1-azido-4-aminobutane;LCZC1219;SCHEMBL13986345;DTXSID40236881;AKOS006309470;BP-29673;MS-22744;HY-108374;CS-0028502;FT-0685279;EN300-142415

Chemical Property of 4-Azidobutan-1-amine

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 75.77000
• Density: g/cm³
• LogP: 1.18866
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 114.090546336
• Heavy Atom Count: 8
• Complexity: 84

Purity/Quality:

97% ^*data from raw suppliers

4-Azidobutylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCN=[N+]=[N-])CN
• Uses: 4-Azidobutylamine is weakly or non-mutagenic to Salmonella typhimurium.

Technology Process of 4-Azidobutan-1-amine

There total 10 articles about 4-Azidobutan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1,4-diazidobutane (24345-72-0) → 4-azidobutan-1-amine (88192-20-5)

Guidance literature:

With hydrogenchloride; triphenylphosphine; In diethyl ether; water; ethyl acetate; at 20 ℃; for 24h;

DOI:10.1016/S0040-4039(01)00282-9

Reference yield: 83.0%

1-azido-4-isocyanatobutane (177489-76-8) → 4-azidobutan-1-amine (88192-20-5)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; for 4h; Heating;

DOI:10.1055/s-1996-4438

Reference yield: 62.0%

N-(4-azidobutyl)phthalimide (66917-06-4) → 4-azidobutan-1-amine (88192-20-5)

Guidance literature:

With hydrazine hydrate; In ethanol; for 24h;

DOI:10.1039/c3ra43415j

upstream raw materials:

1-azido-4-isocyanatobutane

1,4-diazidobutane

N-t-butoxycarbonyl-4-azidobutylamine

1,4-diaminobutane

Downstream raw materials:

putrescine dihydrochloride

N-t-butoxycarbonyl-4-azidobutylamine

N⁶-[1-(4-azidobutyl)]-5'-O-dibenzyloxyphosphoryl-2',3'-didehydro-2',3'-dideoxyadenosine

5'(S)-{N⁴-[1-(4-azidobutyl)]cytosin-1-yl}-1',3'-oxathiolane-2'(R)-carboxylic acid (1R,2S,5R)-menthyl ester