4-C-acetoxymethyl-4,8-anhydro-5,6,7,9-tetra-O-benzyl-2,3-dideoxy-D-glycero-D-ido-nonononitrile

Base Information

• Chemical Name: 4-C-acetoxymethyl-4,8-anhydro-5,6,7,9-tetra-O-benzyl-2,3-dideoxy-D-glycero-D-ido-nonononitrile
• CAS No.: 96455-44-6
• Molecular Formula: C₄₀H₄₃NO₇
• Molecular Weight: 649.784
• Mol file: 96455-44-6.mol

Synonyms:4-C-acetoxymethyl-4,8-anhydro-5,6,7,9-tetra-O-benzyl-2,3-dideoxy-D-glycero-D-ido-nonononitrile

Chemical Property of 4-C-acetoxymethyl-4,8-anhydro-5,6,7,9-tetra-O-benzyl-2,3-dideoxy-D-glycero-D-ido-nonononitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-C-acetoxymethyl-4,8-anhydro-5,6,7,9-tetra-O-benzyl-2,3-dideoxy-D-glycero-D-ido-nonononitrile

There total 2 articles about 4-C-acetoxymethyl-4,8-anhydro-5,6,7,9-tetra-O-benzyl-2,3-dideoxy-D-glycero-D-ido-nonononitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

Acetic acid (3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-2-nitro-tetrahydro-pyran-2-ylmethyl ester (89023-65-4,89023-66-5,89023-69-8,89023-70-1) + acrylonitrile (107-13-1,25014-41-9) → 4-C-acetoxymethyl-4,8-anhydro-5,6,7,9-tetra-O-benzyl-2,3-dideoxy-D-glycero-D-ido-nonononitrile (96455-44-6)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; for 1h; Heating;

DOI:10.1016/S0008-6215(00)90896-6

Reference yield: 45.0%

acrylonitrile (107-13-1,25014-41-9) + 1-O-acetyl-3,4,5,7-tetra-O-benzyl-2-deoxy-2-nitro-α-D-gluco-heptulopyranose (89023-65-4) → 4-C-acetoxymethyl-4,8-anhydro-5,6,7,9-tetra-O-benzyl-2,3-dideoxy-D-glycero-D-ido-nonononitrile (96455-44-6)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; Heating;

DOI:10.1021/ja00300a043

upstream raw materials:

Acetic acid (3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-2-nitro-tetrahydro-pyran-2-ylmethyl ester

acrylonitrile

1-O-acetyl-3,4,5,7-tetra-O-benzyl-2-deoxy-2-nitro-α-D-gluco-heptulopyranose