2-(4-tert-Butyl-benzylsulfanylcarbonyl)-propionic acid ethyl ester

Base Information

• Chemical Name: 2-(4-tert-Butyl-benzylsulfanylcarbonyl)-propionic acid ethyl ester
• CAS No.: 195883-17-1
• Molecular Formula: C₁₇H₂₄O₃S
• Molecular Weight: 308.442
• Mol file: 195883-17-1.mol

Synonyms:2-(4-tert-Butyl-benzylsulfanylcarbonyl)-propionic acid ethyl ester

Chemical Property of 2-(4-tert-Butyl-benzylsulfanylcarbonyl)-propionic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-(4-tert-Butyl-benzylsulfanylcarbonyl)-propionic acid ethyl ester

There total 1 articles about 2-(4-tert-Butyl-benzylsulfanylcarbonyl)-propionic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-tert-butylbenzyl mercaptan (49543-63-7) + potassium ethyl methylmalonate (103362-70-5) → 2-(4-tert-Butyl-benzylsulfanylcarbonyl)-propionic acid ethyl ester (195883-17-1)

Guidance literature:

With oxalyl dichloride; In dichloromethane;

DOI:10.1016/S0040-4039(97)01289-6

Reference yield:

2-(4-tert-Butyl-benzylsulfanylcarbonyl)-propionic acid ethyl ester (195883-17-1) → 3-Bromo-2-(4-tert-butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid (195883-23-9)

Guidance literature:

Multi-step reaction with 2 steps

1: NaH / tetrahydrofuran / Heating

2: BBr₃ / CH₂Cl₂

With boron tribromide; sodium hydride; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0040-4039(97)01289-6

Reference yield:

2-(4-tert-Butyl-benzylsulfanylcarbonyl)-propionic acid ethyl ester (195883-17-1) → [2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionylamino]-acetic acid

Guidance literature:

Multi-step reaction with 4 steps

1: NaH / tetrahydrofuran / Heating

2: BBr₃ / CH₂Cl₂

3: (COCl)2 / CH₂Cl₂

4: CF₃COOH

With oxalyl dichloride; boron tribromide; sodium hydride; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0040-4039(97)01289-6

upstream raw materials:

4-tert-butylbenzyl mercaptan

potassium ethyl methylmalonate

Downstream raw materials:

2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid ethyl ester

3-Bromo-2-(4-tert-butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid ethyl ester

2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid

3-Bromo-2-(4-tert-butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid