2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid

Base Information

• Chemical Name: 2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid
• CAS No.: 195883-21-7
• Molecular Formula: C₁₆H₂₂O₃S
• Molecular Weight: 294.415
• Mol file: 195883-21-7.mol

Synonyms:2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid

Chemical Property of 2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid

There total 3 articles about 2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-tert-butylbenzyl mercaptan (49543-63-7) → 2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid (195883-21-7)

Guidance literature:

Multi-step reaction with 3 steps

1: (COCl)2 / CH₂Cl₂

2: NaH / tetrahydrofuran / Heating

3: BBr₃ / CH₂Cl₂

With oxalyl dichloride; boron tribromide; sodium hydride; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0040-4039(97)01289-6

Reference yield:

2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid ethyl ester (195883-18-2) → 2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid (195883-21-7)

Guidance literature:

With boron tribromide; In dichloromethane;

DOI:10.1016/S0040-4039(97)01289-6

Reference yield:

2-(4-tert-Butyl-benzylsulfanylcarbonyl)-propionic acid ethyl ester (195883-17-1) → 2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid (195883-21-7)

Guidance literature:

Multi-step reaction with 2 steps

1: NaH / tetrahydrofuran / Heating

2: BBr₃ / CH₂Cl₂

With boron tribromide; sodium hydride; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0040-4039(97)01289-6

upstream raw materials:

2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionic acid ethyl ester

4-tert-butylbenzyl mercaptan

2-(4-tert-Butyl-benzylsulfanylcarbonyl)-propionic acid ethyl ester

Downstream raw materials:

[2-(4-tert-Butyl-benzylsulfanylcarbonyl)-2-methyl-propionylamino]-acetic acid tert-butyl ester