C₁₇H₁₈F₃NO₂S₂

Base Information

Chemical Name:C₁₇H₁₈F₃NO₂S₂
CAS No.:1380243-33-3
Molecular Formula:C₁₇H₁₈F₃NO₂S₂
Molecular Weight:389.463
Hs Code.:

C<sub>17</sub>H<sub>18</sub>F<sub>3</sub>NO<sub>2</sub>S<sub>2</sub>

Synonyms:C₁₇H₁₈F₃NO₂S₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₇H₁₈F₃NO₂S₂

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Technology Process of C₁₇H₁₈F₃NO₂S₂

There total 7 articles about C₁₇H₁₈F₃NO₂S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 327-52-6
1-bromo-2,4,5-trifluorobenzene

: 1380243-22-0
C₁₂H₁₅NOS

: 1380243-33-3
C₁₇H₁₈F₃NO₂S₂

Guidance literature:: 1-bromo-2,4,5-trifluorobenzene; With copper(I) bromide dimethylsulfide complex; tert-butylmagnesium bromide; In tetrahydrofuran; at -20 - -5 ℃; for 0.25h; Inert atmosphere;

C₁₂H₁₅NOS; In tetrahydrofuran; for 0.0833333h;

Reference yield: 85.0%

: 327-52-6
1-bromo-2,4,5-trifluorobenzene

: 1380243-21-9
C₁₁H₁₅NO₂S₂

: 1380243-33-3
C₁₇H₁₈F₃NO₂S₂

Guidance literature:: 1-bromo-2,4,5-trifluorobenzene; With isopropylmagnesium bromide; In tetrahydrofuran; at -20 ℃; Inert atmosphere;

With copper(I) bromide dimethylsulfide complex; In tetrahydrofuran; at -5 ℃; for 0.25h; Inert atmosphere;

C₁₁H₁₅NO₂S₂; In tetrahydrofuran; for 0.0833333h;

Reference yield:

: 51786-15-3
4-[(methylsulfanyl)-2-(phenylsulfonyl)amino]butanoic acid

: 1380243-33-3
C₁₇H₁₈F₃NO₂S₂

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium tetrahydroborate; iodine; methanol / tetrahydrofuran / 2 h / 0 - 5 °C / Reflux

2.1: triethylamine / dichloromethane / 4 h / 0 - 20 °C

3.1: sodium hydride / tetrahydrofuran / 0.25 h / 0 °C / Inert atmosphere

4.1: isopropylmagnesium bromide / tetrahydrofuran / -20 °C / Inert atmosphere

4.2: 0.25 h / -5 °C / Inert atmosphere

4.3: 0.08 h

With methanol; sodium tetrahydroborate; iodine; isopropylmagnesium bromide; sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane;