(R)-2-Amino-6-benzyloxycarbonylamino-hexanoic acid 2-trimethylsilanyl-ethyl ester

Base Information

Chemical Name:(R)-2-Amino-6-benzyloxycarbonylamino-hexanoic acid 2-trimethylsilanyl-ethyl ester
CAS No.:343332-53-6
Molecular Formula:C₁₉H₃₂N₂O₄Si
Molecular Weight:380.56
Hs Code.:

Synonyms:(R)-2-Amino-6-benzyloxycarbonylamino-hexanoic acid 2-trimethylsilanyl-ethyl ester

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Chemical Property of (R)-2-Amino-6-benzyloxycarbonylamino-hexanoic acid 2-trimethylsilanyl-ethyl ester

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Technology Process of (R)-2-Amino-6-benzyloxycarbonylamino-hexanoic acid 2-trimethylsilanyl-ethyl ester

There total 1 articles about (R)-2-Amino-6-benzyloxycarbonylamino-hexanoic acid 2-trimethylsilanyl-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 2916-68-9
2-(Trimethylsilyl)ethanol

: 55878-47-2
(R)-6-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoic acid

: 343332-53-6
(R)-2-Amino-6-benzyloxycarbonylamino-hexanoic acid 2-trimethylsilanyl-ethyl ester

Guidance literature:: 2-(Trimethylsilyl)ethanol; (R)-6-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoic acid; With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 22h;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1.5h; Further stages.;
DOI:10.1021/ja005886l

Reference yield: 70.0%

: 343332-76-3
C₃₁H₄₀N₆O₉

: 343332-53-6
(R)-2-Amino-6-benzyloxycarbonylamino-hexanoic acid 2-trimethylsilanyl-ethyl ester

: 343332-82-1
C₅₀H₇₂N₈O₁₂Si

Guidance literature:: With sodium tris(acetoxy)borohydride; N-ethyl-N,N-diisopropylamine; In 1,2-dichloro-ethane; at 20 ℃; for 16h;
DOI:10.1021/ja005886l