10-(dimethylamino)-3-hydroxy-spiro[7H-benzo[c]xanthene-7,1'(3'H)-isobenzofuran]-3'-one

Base Information

• Chemical Name: 10-(dimethylamino)-3-hydroxy-spiro[7H-benzo[c]xanthene-7,1'(3'H)-isobenzofuran]-3'-one
• CAS No.: 131071-73-3
• Molecular Formula: C₂₆H₁₉NO₄
• Molecular Weight: 409.441
• Mol file: 131071-73-3.mol

Synonyms:10-(dimethylamino)-3-hydroxy-spiro[7H-benzo[c]xanthene-7,1'(3'H)-isobenzofuran]-3'-one

Chemical Property of 10-(dimethylamino)-3-hydroxy-spiro[7H-benzo[c]xanthene-7,1'(3'H)-isobenzofuran]-3'-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-(dimethylamino)-3-hydroxy-spiro[7H-benzo[c]xanthene-7,1'(3'H)-isobenzofuran]-3'-one

There total 1 articles about 10-(dimethylamino)-3-hydroxy-spiro[7H-benzo[c]xanthene-7,1'(3'H)-isobenzofuran]-3'-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phthalic anhydride (85-44-9) + 1,6-dihydroxynaphthalene (575-44-0) + 3-Dimethylaminophenol (99-07-0) → 10-(dimethylamino)-3-hydroxy-spiro[7H-benzo[c]xanthene-7,1'(3'H)-isobenzofuran]-3'-one (131071-73-3)

Guidance literature:

phthalic anhydride; 3-Dimethylaminophenol; In toluene; Reflux;

1,6-dihydroxynaphthalene; With zinc(II) chloride; at 160 ℃;

DOI:10.1016/j.bmc.2009.08.037

Reference yield: 76.0%

10-(dimethylamino)-3-hydroxy-spiro[7H-benzo[c]xanthene-7,1'(3'H)-isobenzofuran]-3'-one (131071-73-3) + benzyl bromide (100-39-0) → 10-(dimethylamino)-3-phenylmethoxy-spiro[7hbenzo[c]xanthene-7,1'(3'H)-isobenzofuran]-3'-one (1194732-80-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 19h;

DOI:10.1016/j.bmc.2009.08.037

Reference yield: 65.0%

10-(dimethylamino)-3-hydroxy-spiro[7H-benzo[c]xanthene-7,1'(3'H)-isobenzofuran]-3'-one (131071-73-3) + tert-butylchlorodiphenylsilane (58479-61-1) → C42H37NO4Si

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1246/bcsj.20140303

upstream raw materials:

phthalic anhydride

1,6-dihydroxynaphthalene

3-Dimethylaminophenol

Downstream raw materials:

10-(dimethylamino)-3-phenylmethoxy-spiro[7hbenzo[c]xanthene-7,1'(3'H)-isobenzofuran]-3'-one

10-(dimethylamino)-3-[(4-nitrophenyl)methoxy]-spiro-[7H-benzo[c]xanthene-7,1'(3'H)-isobenzofuran]-3'-one

10-(dimethylamino)-3-[(4-acetoxyphenyl)methoxy]-spiro-[7H-benzo[c]xanthene-7,10-(30H)-isobenzofuran]-30-one