2-[(3R)-pyrrolidin-3-yloxy]benzonitrile maleate

Base Information

Chemical Name:2-[(3R)-pyrrolidin-3-yloxy]benzonitrile maleate
CAS No.:900512-38-1
Molecular Formula:C₄H₄O₄*C₁₁H₁₂N₂O
Molecular Weight:304.302
Hs Code.:

Synonyms:2-[(3R)-pyrrolidin-3-yloxy]benzonitrile maleate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[(3R)-pyrrolidin-3-yloxy]benzonitrile maleate

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Technology Process of 2-[(3R)-pyrrolidin-3-yloxy]benzonitrile maleate

There total 1 articles about 2-[(3R)-pyrrolidin-3-yloxy]benzonitrile maleate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 110-16-7,26099-09-2
maleic acid

: 101469-92-5,83220-73-9
(S)-3-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester

: 900512-38-1
2-[(3R)-pyrrolidin-3-yloxy]benzonitrile maleate

Guidance literature:: salicylonitrile; (S)-3-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester; With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 18h;

With hydrogenchloride; water; In 1,4-dioxane;

maleic acid; In ethyl acetate; at 20 ℃; for 0.5h;