3-Trimethylsilyl-4-pentenoicacid

Base Information

• Chemical Name: 3-Trimethylsilyl-4-pentenoicacid
• CAS No.: 103681-20-5
• Molecular Formula: C₈H₁₆O₂Si
• Molecular Weight: 172.299
• Mol file: 103681-20-5.mol

Synonyms:3-Trimethylsilyl-4-pentenoicacid

Chemical Property of 3-Trimethylsilyl-4-pentenoicacid

Chemical Property:

• PSA: 37.30000
• LogP: 2.35550

Purity/Quality:

98%Min ^*data from raw suppliers

3-TRIMETHYLSILYL-4-PENTENOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Trimethylsilyl-4-pentenoicacid

There total 4 articles about 3-Trimethylsilyl-4-pentenoicacid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

(E)-3-(trimethylsilyl)-2-propenyl acetate (86422-21-1) → 3-Trimethylsilanyl-pent-4-enoic acid (103681-20-5)

Guidance literature:

DOI:10.1016/S0040-4039(00)98900-7

Reference yield:

(2E)-3-(trimethylsilyl)prop-2-en-1-ol (59376-64-6) → 3-Trimethylsilanyl-pent-4-enoic acid (103681-20-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 82 percent / Pyridine / tetrahydrofuran / 0 °C

2: 1.) Zn / THF, HMPA

3: 2.) H₂O, H⁽¹⁺⁾ / 2.) heating

With pyridine; water; hydrogen cation; zinc; In tetrahydrofuran;

DOI:10.1016/S0040-4039(00)98900-7

Reference yield:

(E)-3-[1-(tert-Butyl-dimethyl-silanyloxy)-vinyloxy]-1-trimethylsilanyl-propene (103681-19-2) → 3-Trimethylsilanyl-pent-4-enoic acid (103681-20-5)

Guidance literature:

With water; hydrogen cation; Multistep reaction; 2.) heating;

DOI:10.1016/S0040-4039(00)98900-7

upstream raw materials:

(E)-3-[1-(tert-Butyl-dimethyl-silanyloxy)-vinyloxy]-1-trimethylsilanyl-propene

(E)-3-(trimethylsilyl)-2-propenyl acetate

(2E)-3-(trimethylsilyl)prop-2-en-1-ol

3-Trimethylsilyl-2-propenyl α-bromoacetate

Downstream raw materials:

Chloro-phenylsulfanyl-acetic acid 6-trimethylsilanyl-oct-7-enyl ester

Chloro-phenylsulfanyl-acetic acid 1-methyl-5-trimethylsilanyl-hept-6-enyl ester

Chloro-phenylsulfanyl-acetic acid 5-trimethylsilanyl-hept-6-enyl ester

Chloro-phenylsulfanyl-acetic acid 4-trimethylsilanyl-hex-5-enyl ester

Refernces