8-Methyl-3,4-dihydroquinoline-1(2H)-carbonyl chloride

Base Information

Chemical Name:8-Methyl-3,4-dihydroquinoline-1(2H)-carbonyl chloride
CAS No.:103661-43-4
Molecular Formula:C₁₁H₁₂ClNO
Molecular Weight:209.675
Hs Code.:
DSSTox Substance ID:DTXSID30546749
Wikidata:Q82424658
Mol file:103661-43-4.mol

Synonyms:103661-43-4;8-Methyl-3,4-dihydroquinoline-1(2H)-carbonyl chloride;8-METHYL-3,4-DIHYDRO-2H-QUINOLINE-1-CARBONYL CHLORIDE;1(2H)-Quinolinecarbonyl chloride, 3,4-dihydro-8-methyl- (9CI);SCHEMBL10914380;DTXSID30546749

Suppliers and Price of 8-Methyl-3,4-dihydroquinoline-1(2H)-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 8-Methyl-3,4-dihydroquinoline-1(2H)-carbonyl chloride

Chemical Property:

PSA：20.31000
LogP:3.17140
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:209.0607417
Heavy Atom Count:14
Complexity:231

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=CC=C1)CCCN2C(=O)Cl

Technology Process of 8-Methyl-3,4-dihydroquinoline-1(2H)-carbonyl chloride

There total 2 articles about 8-Methyl-3,4-dihydroquinoline-1(2H)-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-44-5
phosgene

: 52601-70-4
8-methyl-1,2,3,4-tetrahydroquinoline

: 103661-43-4
8-methyl-3,4-dihydroquinoline-1(2H)-carbonyl chloride

Guidance literature:: With pyridine; In dichloromethane; at 0 ℃;
DOI:10.1016/j.bmcl.2009.07.031

Reference yield:

: 52601-70-4
8-methyl-1,2,3,4-tetrahydroquinoline

: 32315-10-9
bis(trichloromethyl) carbonate

: 103661-43-4
8-methyl-3,4-dihydroquinoline-1(2H)-carbonyl chloride

Guidance literature:: bis(trichloromethyl) carbonate; With pyridine; In dichloromethane; at 0 ℃; for 0.0833333h; Inert atmosphere;

8-methyl-1,2,3,4-tetrahydroquinoline; In dichloromethane; at 0 - 20 ℃; for 3h; Inert atmosphere;
DOI:10.1002/anie.201605714