Quinoxaline, 1,2,3,4-tetrahydro-1-propyl- (6CI)

Base Information

• Chemical Name: Quinoxaline, 1,2,3,4-tetrahydro-1-propyl- (6CI)
• CAS No.: 103639-83-4
• Molecular Formula: C₁₁H₁₆N₂
• Molecular Weight: 176.261
• Mol file: 103639-83-4.mol

Synonyms:Quinoxaline, 1,2,3,4-tetrahydro-1-propyl- (6CI);1-PROPYL-1,2,3,4-TETRAHYDROQUINOXALINE

Chemical Property of Quinoxaline, 1,2,3,4-tetrahydro-1-propyl- (6CI)

Chemical Property:

• PSA: 15.27000
• LogP: 2.53150

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Quinoxaline, 1,2,3,4-tetrahydro-1-propyl- (6CI)

There total 3 articles about Quinoxaline, 1,2,3,4-tetrahydro-1-propyl- (6CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-benzenesulfonyl-4-propyl-1,2,3,4-tetrahydro-quinoxaline (7151-46-4) → 1-propyl-1,2,3,4-tetrahydroquinoxaline (103639-83-4)

Guidance literature:

With sulfuric acid;

DOI:10.1021/ja01196a015

Reference yield:

4-propyl-3,4-dihydro-1H-quinoxalin-2-one (99840-78-5) → 1-propyl-1,2,3,4-tetrahydroquinoxaline (103639-83-4)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

DOI:10.1021/jo01084a014

Reference yield:

1,2,3,4-tetrahydroquinoxalin-2-one (59564-59-9) → 1-propyl-1,2,3,4-tetrahydroquinoxaline (103639-83-4)

Guidance literature:

Multi-step reaction with 2 steps

1: Na₂CO₃; ethanol

2: LiAlH₄; diethyl ether

With lithium aluminium tetrahydride; diethyl ether; ethanol; sodium carbonate;

DOI:10.1021/jo01084a014

upstream raw materials:

4-propyl-3,4-dihydro-1H-quinoxalin-2-one

1-benzenesulfonyl-4-propyl-1,2,3,4-tetrahydro-quinoxaline

1,2,3,4-tetrahydroquinoxalin-2-one

Downstream raw materials:

C₂₃H₂₁Cl₂N₃O₂

C₂₂H₂₀Cl₂N₄O₂