(2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)(hexahydropyrrolo[3,4-c]pyrrole-2(1H)-yl)methanone

Base Information

Chemical Name:(2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)(hexahydropyrrolo[3,4-c]pyrrole-2(1H)-yl)methanone
CAS No.:1293284-63-5
Molecular Formula:C₁₅H₁₆FN₅O
Molecular Weight:301.323
Hs Code.:

Synonyms:(2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)(hexahydropyrrolo[3,4-c]pyrrole-2(1H)-yl)methanone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)(hexahydropyrrolo[3,4-c]pyrrole-2(1H)-yl)methanone

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of (2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)(hexahydropyrrolo[3,4-c]pyrrole-2(1H)-yl)methanone

There total 6 articles about (2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)(hexahydropyrrolo[3,4-c]pyrrole-2(1H)-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.27%

: 1293284-63-5
(2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)(hexahydropyrrolo[3,4-c]pyrrole-2(1H)-yl)methanone

Guidance literature:: With hydrogenchloride; In dichloromethane; ethyl acetate; at 20 ℃; for 1h;

Reference yield:

: 186202-73-3
tert-butyl 5-benzylhexahydropyrrolo[3.4-c]pyrrole-2(1H)-carboxylate

: 1293284-63-5
(2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)(hexahydropyrrolo[3,4-c]pyrrole-2(1H)-yl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen / palladium 10% on activated carbon / acetic acid; methanol / 72 h / 3620.13 Torr

2: sodium carbonate / toluene; water / 0 - 20 °C

3: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

With hydrogen; sodium carbonate; trifluoroacetic acid; palladium 10% on activated carbon; In methanol; dichloromethane; water; acetic acid; toluene;

Reference yield:

: 86732-22-1
2-benzyloctahydropyrrolo[3,4-c]pyrrole

: 1293284-63-5
(2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)(hexahydropyrrolo[3,4-c]pyrrole-2(1H)-yl)methanone

Guidance literature:: Multi-step reaction with 4 steps

1: dichloromethane / 24 h / 23 °C

2: hydrogen / palladium 10% on activated carbon / acetic acid; methanol / 72 h / 3620.13 Torr

3: sodium carbonate / toluene; water / 0 - 20 °C

4: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

With hydrogen; sodium carbonate; trifluoroacetic acid; palladium 10% on activated carbon; In methanol; dichloromethane; water; acetic acid; toluene;