Technology Process of 2,3,6-tribromo-4,5-dimethoxybenzyl bromide
There total 6 articles about 2,3,6-tribromo-4,5-dimethoxybenzyl bromide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bromine; iron;
In
acetic acid;
at 70 - 75 ℃;
for 5h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: bromine; acetic acid; iron / 60 °C
2: N-Bromosuccinimide; sulfuric acid / 0 °C
3: sodium tetrahydroborate / methanol / 0 °C
4: phosphorus tribromide; triethylamine / dichloromethane / 0 - 15 °C
With
sodium tetrahydroborate; N-Bromosuccinimide; sulfuric acid; bromine; phosphorus tribromide; iron; acetic acid; triethylamine;
In
methanol; dichloromethane;
DOI:10.1016/j.bmcl.2018.05.022
- Guidance literature:
-
Multi-step reaction with 6 steps
1: bromine / methanol / 0 °C
2: potassium carbonate / N,N-dimethyl-formamide / 20 °C
3: bromine; acetic acid; iron / 60 °C
4: N-Bromosuccinimide; sulfuric acid / 0 °C
5: sodium tetrahydroborate / methanol / 0 °C
6: phosphorus tribromide; triethylamine / dichloromethane / 0 - 15 °C
With
sodium tetrahydroborate; N-Bromosuccinimide; sulfuric acid; bromine; phosphorus tribromide; iron; potassium carbonate; acetic acid; triethylamine;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2018.05.022
