trans-4-(aminomethyl)cyclohexanemethanol hydrochloride

Base Information

• Chemical Name: trans-4-(aminomethyl)cyclohexanemethanol hydrochloride
• CAS No.: 178972-33-3
• Molecular Formula: C₈H₁₇NO*ClH
• Molecular Weight: 179.69
• Mol file: 178972-33-3.mol

Synonyms:trans-4-(aminomethyl)cyclohexanemethanol hydrochloride

Chemical Property of trans-4-(aminomethyl)cyclohexanemethanol hydrochloride

Chemical Property:

Purity/Quality:

95%+ ^*data from raw suppliers

trans-4-(Aminomethyl)cyclohexanemethanolHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-4-(aminomethyl)cyclohexanemethanol hydrochloride

There total 1 articles about trans-4-(aminomethyl)cyclohexanemethanol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methanolic hydrochloric acid + trans-4-aminomethyl-cyclohexyl-carboxylic acid (1197-18-8) → trans-4-(aminomethyl)cyclohexanemethanol hydrochloride (178972-33-3)

Guidance literature:

With borane; In tetrahydrofuran; methanol;

Reference yield: 98.0%

trans-4-(aminomethyl)cyclohexanemethanol hydrochloride (178972-33-3) + di-tert-butyl dicarbonate (24424-99-5) → tert-butyl (((1r,4r)-4-(hydroxymethyl)cyclohexyl)methyl)carbamate (172348-63-9)

Guidance literature:

With sodium carbonate; In 1,4-dioxane; dichloromethane; water;

upstream raw materials:

trans-4-aminomethyl-cyclohexyl-carboxylic acid

Downstream raw materials:

tert-butyl (((1r,4r)-4-(hydroxymethyl)cyclohexyl)methyl)carbamate

Refernces