methyl 2-(1H-1,2,3-benzotriazol-1-yl)-2-ethoxy-N-(3-fluorophenyl)-3-butenimidothioate

Base Information

Chemical Name:methyl 2-(1H-1,2,3-benzotriazol-1-yl)-2-ethoxy-N-(3-fluorophenyl)-3-butenimidothioate
CAS No.:306990-43-2
Molecular Formula:C₁₉H₁₉FN₄OS
Molecular Weight:370.45
Hs Code.:

Synonyms:methyl 2-(1H-1,2,3-benzotriazol-1-yl)-2-ethoxy-N-(3-fluorophenyl)-3-butenimidothioate

Suppliers and Price of methyl 2-(1H-1,2,3-benzotriazol-1-yl)-2-ethoxy-N-(3-fluorophenyl)-3-butenimidothioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-(1H-1,2,3-benzotriazol-1-yl)-2-ethoxy-N-(3-fluorophenyl)-3-butenimidothioate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-(1H-1,2,3-benzotriazol-1-yl)-2-ethoxy-N-(3-fluorophenyl)-3-butenimidothioate

There total 3 articles about methyl 2-(1H-1,2,3-benzotriazol-1-yl)-2-ethoxy-N-(3-fluorophenyl)-3-butenimidothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 404-72-8
3-fluorophenyl isothiocyanate

: 161607-20-1
3-(benzotriazol-1-yl)-3-ethoxy-1-propene

: 74-88-4
methyl iodide

: 306990-43-2
methyl 2-(1H-1,2,3-benzotriazol-1-yl)-2-ethoxy-N-(3-fluorophenyl)-3-butenimidothioate

Guidance literature:: 3-(benzotriazol-1-yl)-3-ethoxy-1-propene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.166667h;

3-fluorophenyl isothiocyanate; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

methyl iodide; In tetrahydrofuran; hexane; at -78 - 20 ℃; Further stages.;
DOI:10.1021/jo001159x

Reference yield:

: 95-14-7,27556-51-0
1,2,3-Benzotriazole

: 306990-43-2
methyl 2-(1H-1,2,3-benzotriazol-1-yl)-2-ethoxy-N-(3-fluorophenyl)-3-butenimidothioate

Guidance literature:: Multi-step reaction with 2 steps

1.1: hexane / 18 h / Heating

2.1: n-BuLi / tetrahydrofuran; hexane / 0.17 h / -78 °C

2.2: tetrahydrofuran; hexane / 0.5 h / -78 °C

2.3: 60 percent / tetrahydrofuran; hexane / -78 - 20 °C

With n-butyllithium; In tetrahydrofuran; hexane;
DOI:10.1021/jo001159x

Reference yield:

: 3054-95-3
acrylaldehyde diethyl acetal

: 306990-43-2
methyl 2-(1H-1,2,3-benzotriazol-1-yl)-2-ethoxy-N-(3-fluorophenyl)-3-butenimidothioate

Guidance literature:: Multi-step reaction with 2 steps

1.1: hexane / 18 h / Heating

2.1: n-BuLi / tetrahydrofuran; hexane / 0.17 h / -78 °C

2.2: tetrahydrofuran; hexane / 0.5 h / -78 °C

2.3: 60 percent / tetrahydrofuran; hexane / -78 - 20 °C

With n-butyllithium; In tetrahydrofuran; hexane;
DOI:10.1021/jo001159x