N-[(1R,2R)-2-(4-Amino-phenyl)-2-hydroxy-1-hydroxymethyl-ethyl]-formamide

Base Information

Chemical Name:N-[(1R,2R)-2-(4-Amino-phenyl)-2-hydroxy-1-hydroxymethyl-ethyl]-formamide
CAS No.:51458-27-6
Molecular Formula:C₁₀H₁₄N₂O₃
Molecular Weight:210.233
Hs Code.:

Synonyms:N-[(1R,2R)-2-(4-Amino-phenyl)-2-hydroxy-1-hydroxymethyl-ethyl]-formamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[(1R,2R)-2-(4-Amino-phenyl)-2-hydroxy-1-hydroxymethyl-ethyl]-formamide

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Technology Process of N-[(1R,2R)-2-(4-Amino-phenyl)-2-hydroxy-1-hydroxymethyl-ethyl]-formamide

There total 2 articles about N-[(1R,2R)-2-(4-Amino-phenyl)-2-hydroxy-1-hydroxymethyl-ethyl]-formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 23885-67-8
N-[(1R,2R)-2-Hydroxy-1-hydroxymethyl-2-(4-nitro-phenyl)-ethyl]-formamide

: 51458-27-6
N-[(1R,2R)-2-(4-Amino-phenyl)-2-hydroxy-1-hydroxymethyl-ethyl]-formamide

Guidance literature:: With hydrogen; platinum(IV) oxide; for 4h; Ambient temperature;
DOI:10.1016/0040-4039(90)87038-2

Reference yield:

: 119-62-0,716-61-0,2792-51-0,2792-52-1,2964-48-9,3689-55-2,63526-31-8,71115-69-0,140694-64-0
D-threo-2-amino-1(4-nitrophenyl)-1,3-propanediol

: 51458-27-6
N-[(1R,2R)-2-(4-Amino-phenyl)-2-hydroxy-1-hydroxymethyl-ethyl]-formamide

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / 2 h / 100 °C

2: 100 percent / H₂ / PtO₂ / 4 h / Ambient temperature

With hydrogen; platinum(IV) oxide;
DOI:10.1016/0040-4039(90)87038-2

Reference yield: 31.0%

: 51458-27-6
N-[(1R,2R)-2-(4-Amino-phenyl)-2-hydroxy-1-hydroxymethyl-ethyl]-formamide

: 129413-12-3
(2R,3R)-2-formylamino-3-(4-hydroxyphenyl)-1,3-propanediol

Guidance literature:: With sulfuric acid; sodium nitrite; 1.) 0 deg C; 2.) pH 6 (NaHCO₃), 75-80 deg C, 30 min;
DOI:10.1016/0040-4039(90)87038-2