Chroman-6-carboxylic acid

Base Information

Chemical Name:Chroman-6-carboxylic acid
CAS No.:103203-84-5
Molecular Formula:C₁₀H₁₀O₃
Molecular Weight:178.188
Hs Code.:2932999099
DSSTox Substance ID:DTXSID00424707
Wikidata:Q72460783
Mol file:103203-84-5.mol

Synonyms:Chroman-6-carboxylic acid;103203-84-5;3,4-dihydro-2H-chromene-6-carboxylic acid;3,4-dihydro-2H-1-benzopyran-6-carboxylic acid;6-chromanecarboxylic acid;CHROMAN-6-CARBOXYLICACID;chromane-6-carboxylic acid;DIMETHYLBRASSYLATE;SCHEMBL875455;DTXSID00424707;CHEBI:194662;IFKANGOXGBPILW-UHFFFAOYSA-N;MFCD08146590;STK692687;6-Chromanecarboxylic acid, AldrichCPR;AKOS000111874;AS-58537;BB 0254808;CS-0038799;FT-0729003;EN300-67358;A896583;Z730726766

Suppliers and Price of Chroman-6-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Chroman-6-carboxylicAcid
100mg
$ 65.00

SynQuest Laboratories
Chroman-6-carboxylicacid
1 g
$ 480.00

SynQuest Laboratories
Chroman-6-carboxylicacid
250 mg
$ 176.00

Matrix Scientific
Chroman-6-carboxylic acid
500mg
$ 155.00

Crysdot
Chroman-6-carboxylicacid 95+%
5g
$ 508.00

Chemenu
Chroman-6-carboxylicacid 95%
5g
$ 480.00

ChemBridge Corporation
6-chromanecarboxylicacid 95%
200 μmol
$ 84.00

ChemBridge Corporation
6-chromanecarboxylicacid 95%
1 g
$ 185.00

Azepine
3,4-dihydro-2H-1-benzopyran-6-carboxylicacid 95
1 g
$ 290.00

Apolloscientific
Chroman-6-carboxylic acid
250mg
$ 149.00

Total 16 raw suppliers

Chemical Property of Chroman-6-carboxylic acid

Chemical Property:

Vapor Pressure:1.42E-05mmHg at 25°C
Melting Point:148-150°C
Refractive Index:1.586
Boiling Point:352.5°Cat760mmHg
PKA:4.53±0.20(Predicted)
Flash Point:145.2°C
PSA：46.53000
Density:1.274g/cm³
LogP:1.70980
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:178.062994177
Heavy Atom Count:13
Complexity:202

Purity/Quality:

97% ^*data from raw suppliers

Chroman-6-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,Xn
Statements: 36/37/38-22
Safety Statements: 22-26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C=CC(=C2)C(=O)O)OC1
Uses Chroman-6-carboxylic Acid is used for preparation and amidation in sythesis of reactive fluorescent stains.

Technology Process of Chroman-6-carboxylic acid

There total 2 articles about Chroman-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 58621-52-6
1-<6-(3,4-dihydro-2H-1-benzopyranyl)>ethanone

: 103203-84-5
6-(3,4-dihydro-1H-1-benzopyranyl)carboxylic acid

Guidance literature:: With sodium hypochlorite; In water; at 55 ℃; for 2h;
DOI:10.1016/j.bmc.2006.09.019

Reference yield:

: 493-08-3
chromane

: 103203-84-5
6-(3,4-dihydro-1H-1-benzopyranyl)carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / aluminum trichloride / CH₂Cl₂ / 0.5 h / -10 °C

2: 82 percent / sodium hypochlorite / H₂O / 2 h / 55 °C

With sodium hypochlorite; aluminium trichloride; In dichloromethane; water;
DOI:10.1016/j.bmc.2006.09.019