4-Nitroamphetamine

Base Information

• Chemical Name: 4-Nitroamphetamine
• CAS No.: 13026-03-4
• Molecular Formula: C₉H₁₂N₂O₂
• Molecular Weight: 180.206
• Mol file: 13026-03-4.mol

Synonyms:4-Nitroamphetamine

Chemical Property of 4-Nitroamphetamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Nitroamphetamine

There total 7 articles about 4-Nitroamphetamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

1-(4-nitrophenyl)propan-2-one (5332-96-7) + ammonium acetate (631-61-8,92206-38-7) → 4-Nitroamphetamine (13026-03-4)

Guidance literature:

With hydrogenchloride; sodium cyanoborohydride; In methanol; at 20 ℃; for 24h;

DOI:10.1002/adsc.202100351

Reference yield:

2-amino-1-phenylpropane (60-15-1,156-34-3,51-64-9,300-62-9,17108-96-2,96332-84-2) → 4-Nitroamphetamine (13026-03-4)

Guidance literature:

With nitric acid; at -15 ℃;

DOI:10.1021/ja01211a005

Reference yield:

1-Methyl-2-(4-nitro-phenyl)-ethylideneamine (144380-89-2) → 4-Nitroamphetamine (13026-03-4)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 3h;

DOI:10.1039/c1ob06251d

upstream raw materials:

2-amino-1-phenylpropane

1-(4-nitrophenyl)propan-2-one

1-Methyl-2-(4-nitro-phenyl)-ethylideneamine

ammonium acetate

Downstream raw materials:

N-<1-(4-nitrophenyl)-2-propyl>nicotinamide chloride

(2-Benzhydryloxy-ethyl)-[1-methyl-2-(4-nitro-phenyl)-ethyl]-amine